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Article
Open AccessLoss of β-arrestin2 aggravated condylar cartilage degeneration at the early stage of temporomandibular joint osteoarthritis
Temporomandibular joint osteoarthritis (TMJOA) is a chronic degenerative joint disorder characterized by extracellular matrix degeneration and inflammatory response of condylar cartilage. β-arrestin2 is an imp...
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Article
Open AccessThe P38MAPK/ATF2 signaling pathway is involved in PND in mice
Accumulating evidence indicates that microglia-mediated neuroinflammation in the hippocampus contributes to the development of perioperative neurocognitive disorder (PND). P38MAPK, a point of convergence for d...
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Article
The Enhanced Optical Chirality Induced by Surface Plasmons in Achiral Magnetoplasmonic Nanostructures
We show theoretically that the enhanced optical chirality in the achiral magnetoplasmonic nanostructures including dual-metallic grating (DMG) structure and single-metallic grating (SMG) structure under linear...
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Article
Open AccessLOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling
Temporomandibular joint OA (TMJOA) is a common degenerative joint disease, leads to structural damage and ultimately loss of function. Matrix degradation is one of the first pathogenesis during the progression...
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Article
Open AccessBRD4 inhibition alleviates mechanical stress-induced TMJ OA-like pathological changes and attenuates TREM1-mediated inflammatory response
The aim of this paper was to investigate the protective effects of bromodomain containing 4 (BRD4) inhibition on the temporomandibular joint osteoarthritis (TMJ OA) induced by compressive mechanical stress and...
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Article
Genetic Diversity and Population Structure of Broomcorn Sorghum Investigated with Simple Sequence Repeat Markers
In order to study the genetic diversity and population structure of broomcorn, a special type of sorghum for broom making, a total of 140 accessions of sorghum varieties including broomcorn (72), half-broomcor...
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Article
Open AccessImportant roles of C-terminal residues in degradation of capsid protein of classical swine fever virus
Capsid (C) protein plays an important role in the replication of classical swine fever virus (CSFV). The ubiquitin proteasome system (UPS) involves in replication of many viruses via modulation of viral protei...
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Article
Fine map** of qGW1, a major QTL for grain weight in sorghum
We detected seven QTLs for 100-grain weight in sorghum using an F 2 population, and delimited qGW1 ...