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  1. Article

    Open Access

    Real world predictors of response and 24-month survival in high-grade TP53-mutated myeloid neoplasms

    Current therapies for high-grade TP53-mutated myeloid neoplasms (≥10% blasts) do not offer a meaningful survival benefit except allogeneic stem cell transplantation in the minority who achieve a complete response...

    Amandeep Kaur, Alexandra E. Rojek, Emily Symes, Mariam T. Nawas… in Blood Cancer Journal (2024)

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    Article

    EZR-ROS1 fusion renal cell carcinoma mimicking urothelial carcinoma: report of a previously undescribed gene fusion in renal cell carcinoma

    A subset of renal cell carcinomas harbor gene fusions, and we report the first case of an EZR-ROS1 fusion in renal cell carcinoma. A 47-year-old female presented with hematuria and a mass involving the renal pelv...

    Antic Tatjana, Melissa Y. Tjota, Peter H. O’Donnell, Scott E. Eggener… in Virchows Archiv (2022)

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    Article

    The Role of Dendritic Cells and Monocytes in the Maintenance and Loss of Respiratory Tolerance

    Promoting tolerance to inhaled antigens is an active area of study with the potential to benefit the millions of Americans currently suffering from respiratory allergies and asthma. Interestingly, not all indi...

    Cara L. Hrusch, Melissa Y. Tjota, Anne I. Sperling in Current Allergy and Asthma Reports (2014)

  4. No Access

    Article

    Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation

    Atopic asthma is an inflammatory pulmonary disease associated with Th2 adaptive immune responses triggered by innocuous antigens. While dendritic cells (DCs) are known to shape the adaptive immune response, th...

    Jesse W. Williams, Melissa Y. Tjota, Bryan S. Clay… in Nature Communications (2013)