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  1. Article

    Open Access

    Detecting lesion-specific ischemia in patients with coronary artery disease with computed tomography fractional flow reserve measured at different sites

    Whether a stenosis can cause hemodynamic lesion-specific ischemia is critical for the treatment decision in patients with coronary artery disease (CAD). Based on coronary computed tomography angiography (CCTA)...

    Zhaoxi Cai, Taihui Yu, Zehong Yang, Huijun Hu, Yongqing Lin in BMC Medical Imaging (2023)

  2. Article

    Open Access

    A radiomics model for predicting the response to methylprednisolone in brain necrosis after radiotherapy for nasopharyngeal carcinoma

    Methylprednisolone is recommended as the front-line therapy for radiation-induced brain necrosis (RN) after radiotherapy for nasopharyngeal carcinoma. However, some patients fail to benefit from methylpredniso...

    **aohuang Zhuo, Huiying Zhao, Meiwei Chen, Youqing Mu, Yi Li in Radiation Oncology (2023)

  3. Article

    Open Access

    Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis

    Inactivation of the tumor suppressor p53 is critical for pathogenesis of glioma, in particular glioblastoma multiforme (GBM). MDM2, the main negative regulator of p53, binds to and forms a stable complex with ...

    Jiacheng Lou, Yuchao Hao, Kefeng Lin, Yizhu Lyu, Meiwei Chen, Han Wang in Molecular Cancer (2020)