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Article
Open AccessDetecting lesion-specific ischemia in patients with coronary artery disease with computed tomography fractional flow reserve measured at different sites
Whether a stenosis can cause hemodynamic lesion-specific ischemia is critical for the treatment decision in patients with coronary artery disease (CAD). Based on coronary computed tomography angiography (CCTA)...
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Article
Open AccessA radiomics model for predicting the response to methylprednisolone in brain necrosis after radiotherapy for nasopharyngeal carcinoma
Methylprednisolone is recommended as the front-line therapy for radiation-induced brain necrosis (RN) after radiotherapy for nasopharyngeal carcinoma. However, some patients fail to benefit from methylpredniso...
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Article
Open AccessCircular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis
Inactivation of the tumor suppressor p53 is critical for pathogenesis of glioma, in particular glioblastoma multiforme (GBM). MDM2, the main negative regulator of p53, binds to and forms a stable complex with ...