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Article
Open AccessNovel role for mineralocorticoid receptors in control of a neuronal phenotype
Mineralocorticoid receptors (MRs) in the brain play a role in learning and memory, neuronal differentiation, and regulation of the stress response. Within the hippocampus, the highest expression of MRs is in a...
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Article
Caffeine-induced synaptic potentiation in hippocampal CA2 neurons
A1 adenosine receptor is antagonized by caffeine and is highly expressed in the CA2 layer of rodent hippocampus. This study now shows that caffeine can induce CA2 synaptic potentiation in a dosage-dependent ma...
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Article
Rapid activity-induced transcription of Arc and other IEGs relies on poised RNA polymerase II
Immediate early genes are rapidly transcribed in response to neuronal activity, but the underlying mechanism is unclear. The authors show that this rapid transcription is mediated by a stalled RNA polymerase I...
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Chapter
Rapid Nuclear Responses to Action Potentials