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  1. Article

    Open Access

    A cross-cohort computational framework to trace tumor tissue-of-origin based on RNA sequencing

    Carcinoma of unknown primary (CUP) is a type of metastatic cancer with tissue-of-origin (TOO) unidentifiable by traditional methods. CUP patients typically have poor prognosis but therapy targeting the origina...

    Binsheng He, Hongmei Sun, Meihua Bao, Haigang Li, Jianjun He in Scientific Reports (2023)

  2. Article

    Open Access

    LncRNA FAS-AS1 upregulated by its genetic variation rs6586163 promotes cell apoptosis in nasopharyngeal carcinoma through regulating mitochondria function and Fas splicing

    Nasopharyngeal carcinoma (NPC) is a common head and neck malignant with a high incidence in Southern China. Genetic aberrations play a vital role in the pathogenesis, progression and prognosis of NPC. In the p...

    Zhen Guo, ZiBo Li, MengLing Zhang, MeiHua Bao, BinSheng He in Scientific Reports (2023)

  3. Article

    Open Access

    The ferroptosis signature predicts the prognosis and immune microenvironment of nasopharyngeal carcinoma

    Nasopharyngeal carcinoma (NPC) is a cancer with a high metastatic rate and poor prognosis. Growing studies suggest that ferroptosis take part in the development of tumours. At the same time, the connection bet...

    Ji Zhou, Tianyao Guo, Lin Zhou, Meihua Bao, Lin Wang, Wenhu Zhou in Scientific Reports (2023)