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Article
Engineering active sites on hierarchical transition bimetal oxyhydride/bicarbonate heterostructure for oxygen evolution catalysis in seawater splitting
Designing efficient and stable electrocatalysts to improve the oxygen evolution reaction (OER) with slow reaction kinetics is essential to improve hydrogen production from electrochemical water splitting. This...
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Article
In Vitro Assessment of Transporter Mediated Perpetrator DDIs for Several Hepatitis C Virus Direct-Acting Antiviral Drugs and Prediction of DDIs with Statins Using Static Models
Inhibitory effects of asunaprevir, daclatasvir, grazoprevir, paritaprevir, simeprevir, and voxilaprevir, direct-acting antiviral (DAA) drugs for the treatment of chronic hepatitis C virus (HCV) infection, were...
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Chapter and Conference Paper
A Survey of Cloud Computing
Recently, Cloud computing has become a very attractive computing paradigm which aims to provide reliable and customized computing environments for widespread Internet users. In our paper, we give a survey of c...
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Article
Genetic regulators of large-scale transcriptional signatures in cancer
Gene expression signatures encompassing dozens to hundreds of genes have been associated with many important parameters of cancer, but mechanisms of their control are largely unknown. Here we present a method ...
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Article
Identification of PRC1 as the p53 target gene uncovers a novel function of p53 in the regulation of cytokinesis
Our previous studies conducted in MCF7-ptsp53 cells have demonstrated that overexpression of the wild-type (wt) p53 at permissive temperature 32°C leads to growth arrest at the G2/M phase of the cell cycle. To...
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Article
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. Oral administration of BBR in 32 hypercholesterolemic patients for 3 months reduced serum cholesterol b...
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Article
Induction of S100A9 Gene Expression by Cytokine Oncostatin M in Breast Cancer Cells Through the STAT3 Signaling Cascade
Cytokine oncostatin M (OM) strongly inhibits the growth of MCF-7 breast cancer cells through the STAT3 signaling pathway. We have performed cDNA microarray analyses to identify novel OM-regulated genes in MCF-...