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  1. Article

    Open Access

    Biosynthesis of gold nanoparticles using leaf extract of Dittrichia viscosa and in vivo assessment of its anti-diabetic efficacy

    Several studies have reported the anti-diabetic effect of biologically synthesized gold nanoparticles (AuNPs). This study was designed to investigate the in vivo anti-diabetic activity of AuNPs synthesized usi...

    Sanaa Ayyoub, Bahaa Al-Trad… in Drug Delivery and Translational Research (2022)

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  2. Article

    Open Access

    Gold nanoparticles attenuate albuminuria by inhibiting podocyte injury in a rat model of diabetic nephropathy

    Several recent studies have reported that gold nanoparticles (AuNPs) attenuate hyperglycemia in diabetic animal models without any observed side effects. The present study was intended to provide insight into ...

    Ghada Alomari, Bahaa Al-Trad… in Drug Delivery and Translational Research (2020)

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  3. Article

    Open Access

    Integrating morphological characters, molecular markers, and distribution patterns to assess the identity of Blepharis species from Jordan

    Blepharis constitutes an important part of the vegetation of the Jordanian arid and semi-arid regions, yet whether one or more species of this genus occurs in the Jordanian area is uncertain. We addressed this qu...

    Riyadh Muhaidat, Mohammad H. Brake, Mazhar Al Zoubi… in Botanical Studies (2018)

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  4. No Access

    Article

    Osteopontin (OPN) Isoforms, Diabetes, Obesity, and Cancer; What Is One Got to Do with the Other? A New Role for OPN

    Alternative splicing of osteopontin (OPN) produces three isoforms: OPNa, OPNb, and OPNc. The aims of this study were to examine the expression profile of OPN isoforms in sera from patients with pancreatic lesi...

    Konrad Sarosiek, Elizabeth Jones, Galina Chipitsyna… in Journal of Gastrointestinal Surgery (2015)

  5. No Access

    Article

    Overexpressing TNF-Alpha in Pancreatic Ductal Adenocarcinoma Cells and Fibroblasts Modifies Cell Survival and Reduces Fatty Acid Synthesis via Downregulation of Sterol Regulatory Element Binding Protein-1 and Activation of Acetyl CoA Carboxylase

    The effect of tumor necrosis factor-alpha (TNF-α) gene delivery has been suggested as a potentially useful therapeutic approach to improve the chemotherapeutic treatment of patients with pancreatic ductal aden...

    Mazhar Al-Zoubi, Galina Chipitsyna, Shivam Saxena… in Journal of Gastrointestinal Surgery (2014)

  6. No Access

    Article

    Clinical Significance of Serum COL6A3 in Pancreatic Ductal Adenocarcinoma

    Type VI collagen (COL6) forms a microfibrillar network often associated with type I collagen and constitutes a major component of the desmoplastic reaction in pancreatic ductal adenocarcinoma (PDA). We have de...

    Christopher Y. Kang, Jonathan Wang… in Journal of Gastrointestinal Surgery (2014)