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  1. Article

    Open Access

    Data-driven regularization lowers the size barrier of cryo-EM structure determination

    Macromolecular structure determination by electron cryo-microscopy (cryo-EM) is limited by the alignment of noisy images of individual particles. Because smaller particles have weaker signals, alignment errors...

    Dari Kimanius, Kiarash Jamali, Max E. Wilkinson, Sofia Lövestam in Nature Methods (2024)