17 Result(s)
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Mauri A. Kostiainen
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Article
Genetically encoded protein crystals by hierarchical design
Three protein interaction surfaces are computationally designed into one protein subunit to enable their accurate assembly into three-dimensional crystals with user-specified lattice architectures.
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Article
Open AccessDNA-origami-directed virus capsid polymorphism
Viral capsids can adopt various geometries, most iconically characterized by icosahedral or helical symmetries. Importantly, precise control over the size and shape of virus capsids would have advantages in th...
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Open AccessRepurposing host-guest chemistry to sequester virulence and eradicate biofilms in multidrug resistant Pseudomonas aeruginosa and Acinetobacter baumannii
The limited diversity in targets of available antibiotic therapies has put tremendous pressure on the treatment of bacterial pathogens, where numerous resistance mechanisms that counteract their function are b...
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Article
Open AccessFoam-formed biocomposites based on cellulose products and lignin
Foam-formed cellulose biocomposites are a promising technology for develo** lightweight and sustainable packaging materials. In this work, we produce and characterize biocomposite foams based on methylcellul...
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Protocol
Protein Coating of DNA Origami
DNA has emerged as a common technique to create custom two- (2D) and three-dimensional (3D) structures at the nanoscale. These DNA nanostructures have already proven useful in development of many biotechnolo...
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Protocol
Electrostatic Self-Assembly of Protein Cage Arrays
Protein and peptide cages are nanoscale containers, which are of particular interest in nanoscience due to their well-defined dimensions and enclosed central cavities that can be filled with material that is p...
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Article
De novo nanomaterial crystals from DNA frameworks
Programmable DNA building blocks hosting diverse nano-objects assemble into three-dimensional nanoparticle lattices whose geometry is determined by the shape and valence of the DNA block.
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Open AccessDNA nanostructure-directed assembly of metal nanoparticle superlattices
Structural DNA nanotechnology provides unique, well-controlled, versatile, and highly addressable motifs and templates for assembling materials at the nanoscale. These methods to build from the bottom-up using...
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Protocol
Packaging DNA Origami into Viral Protein Cages
The DNA origami technique is a widely used method to create customized, complex, spatially well-defined two-dimensional (2D) and three-dimensional (3D) DNA nanostructures. These structures have huge potential ...
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Nanometrology and super-resolution imaging with DNA
Structural DNA nanotechnology is revolutionizing the ways researchers construct arbitrary shapes and patterns in two and three dimensions on the nanoscale. Through Watson–Crick base pairing, DNA can be program...
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DNA origami: The bridge from bottom to top
Over the last decade, DNA origami has matured into one of the most powerful bottom-up nanofabrication techniques. It enables both the fabrication of nanoparticles of arbitrary two-dimensional or three-dimensio...
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Article
Open AccessCooperative colloidal self-assembly of metal-protein superlattice wires
Material properties depend critically on the packing and order of constituent units throughout length scales. Beyond classically explored molecular self-assembly, structure formation in the nanoparticle and co...
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Automated design of DNA origami
A top-down computational method enables fabrication of DNA objects in any shape.
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Open AccessOne-step large-scale deposition of salt-free DNA origami nanostructures
DNA origami nanostructures have tremendous potential to serve as versatile platforms in self-assembly -based nanofabrication and in highly parallel nanoscale patterning. However, uniform deposition and reliabl...
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Open AccessSelf-assembly and modular functionalization of three-dimensional crystals from oppositely charged proteins
Multicomponent crystals and nanoparticle superlattices are a powerful approach to integrate different materials into ordered nanostructures. Well-developed, especially DNA-based, methods for their preparation ...
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Article
Electrostatic assembly of binary nanoparticle superlattices using protein cages
Binary nanoparticle superlattices are periodic nanostructures with lattice constants much shorter than the wavelength of light1,2 and could be used to prepare multifunctional metamaterials3,4. Such superlattices ...
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Self-assembly and optically triggered disassembly of hierarchical dendron–virus complexes
Nature offers a vast array of biological building blocks that can be combined with synthetic materials to generate a variety of hierarchical architectures. Viruses are particularly interesting in this respect ...
