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Article
Open AccessThe ecology, subsistence and diet of ~45,000-year-old Homo sapiens at Ilsenhöhle in Ranis, Germany
Recent excavations at Ranis (Germany) identified an early dispersal of Homo sapiens into the higher latitudes of Europe by 45,000 years ago. Here we integrate results from zooarchaeology, palaeoproteomics, sedime...
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Article
Open AccessAcute compartment syndrome of the thigh after total knee arthroplasty: a case report
Acute compartment syndrome of the thigh after total knee arthroplasty is a rarely described complication. After the assessment of the diagnosis, immediate surgical intervention is necessary to prevent further ...
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Article
Open AccessFast-Track-Endoprothetik
Wesentliche Bestandteile von Fast-Track- oder Enhanced-Recovery-Programmen in der Endoprothetik sind die Optimierung der interdisziplinär-organisatorischen Abläufe sowie der prä-, intra- und postoperativen Vor...
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Article
Open AccessNavigation und Robotik – status präsens und zukünftige Implikationen
Sowohl Navigationssysteme als auch die Robotik ermöglichen eine höhere Präzision bei der Implantation eines künstlichen Kniegelenkes. Eine Verbesserung der klinischen Ergebnisse kann dadurch aber nicht erreich...
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Article
Open AccessHomo sapiens reached the higher latitudes of Europe by 45,000 years ago
The Middle to Upper Palaeolithic transition in Europe is associated with the regional disappearance of Neanderthals and the spread of Homo sapiens. Late Neanderthals persisted in western Europe several millennia ...
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Article
Open AccessThe impact of primary total hip and knee replacement on frailty: an observational prospective analysis
Osteoarthritis is a prevalent condition in frail older adults that requires hip or knee replacement in many patients. The aim of the study was to determine the impact of hip and knee arthroplasty on frailty.
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Article
Influence of bone mineral density on femoral stem subsidence after cementless THA
Femoral stem subsidence can lead to aseptic loosening after total hip arthroplasty (THA). Low bone mineral density (BMD) is a risk factor for stem subsidence as it can affect the initial stability and osteoint...
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Article
Open AccessBetter early outcome with enhanced recovery total hip arthroplasty (ERAS-THA) versus conventional setup in randomized clinical trial (RCT)
Numbers of total hip arthroplasty (THA) are steadily rising and patients expect faster mobility without pain postoperatively. The aim of enhanced recovery after Surgery (ERAS) programs in a multidisciplinary s...
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Article
Open AccessArthrosis diagnosis and treatment recommendations in clinical practice: an exploratory investigation with the generative AI model GPT-4
The spread of artificial intelligence (AI) has led to transformative advancements in diverse sectors, including healthcare. Specifically, generative writing systems have shown potential in various applications...
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Article
Open AccessThe impact of elective total hip and knee arthroplasty on physical performance in orthogeriatric patients: a prospective intervention study
Osteoarthritis is a prevalent condition in older adults that leads to reduced physical function in many patients and ultimately requires hip or knee replacement. The aim of the study was to determine the impac...
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Article
Open AccessDelay of total joint replacement is associated with a higher 90-day revision rate and increased postoperative complications
Delay of elective surgeries, such as total joint replacement (TJR), is a common procedure in the current pandemic. In trauma surgery, postponement is associated with increased complication rates. This study ai...
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Article
Open AccessAncient human DNA recovered from a Palaeolithic pendant
Artefacts made from stones, bones and teeth are fundamental to our understanding of human subsistence strategies, behaviour and culture in the Pleistocene. Although these resources are plentiful, it is impossi...
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Article
Open AccessIsokinetic knee muscle strength comparison after enhanced recovery after surgery (ERAS) versus conventional setup in total knee arthroplasty (TKA): a single blinded prospective randomized study
Total knee arthroplasty (TKA) combined with the concept of enhanced recovery is of continued worldwide interest, as it is reported to improve early functional outcome and treatment quality without increasing c...
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Chapter and Conference Paper
Combining Experiments with Agent-Based Modeling: Benefits for Experimental Management Accounting Research
Laboratory experiments are among the most frequently used methods in management accounting research because they offer high internal validity, enabling the examination of causal relationships. However, experim...
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Article
Open AccessSpecial orthopaedic geriatrics (SOG) - a new multiprofessional care model for elderly patients in elective orthopaedic surgery: a study protocol for a prospective randomized controlled trial of a multimodal intervention in frail patients with hip and knee replacement
Due to demographic change, the number of older people in Germany and worldwide will continue to rise in the coming decades. As a result, the number of elderly and frail patients undergoing total hip and knee a...
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Article
Open AccessGenetic insights into the social organization of Neanderthals
Genomic analyses of Neanderthals have previously provided insights into their population history and relationship to modern humans1–8, but the social organization of Neanderthal communities remains poorly underst...
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Article
Open AccessExtended longevity of DNA preservation in Levantine Paleolithic sediments, Sefunim Cave, Israel
Paleogenomic research can elucidate the evolutionary history of human and faunal populations. Although the Levant is a key land-bridge between Africa and Eurasia, thus far, relatively little ancient DNA data h...
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Article
Open AccessHospital frailty risk score predicts adverse events in spine surgery
The Hospital Frailty Risk Score (HFRS) is derived from routinely collected data and validated as a geriatric risk stratification tool. This study aimed to evaluate the utility of the HFRS as a predictor for po...
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Article
Open AccessAncient genomes from the last three millennia support multiple human dispersals into Wallacea
Previous research indicates that human genetic diversity in Wallacea—islands in present-day Eastern Indonesia and Timor-Leste that were never part of the Sunda or Sahul continental shelves—has been shaped by c...
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Article
Open AccessDifferences in femoral component subsidence rate after THA using an uncemented collarless femoral stem: full weight-bearing with an enhanced recovery rehabilitation versus partial weight-bearing
Femoral component subsidence is a known risk factor for early failure of total hip arthroplasty (THA) using cementless stems. The aim of the study was to compare an enhanced recovery concept with early full we...
