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  1. Article

    Open Access

    A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)

    Patients with cancer are at increased risk of hospitalisation and mortality following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV-2 phenotype evolution in pati...

    Thomas Starkey, Maria C. Ionescu, Michael Tilby, Martin Little in Scientific Reports (2023)

  2. Article

    Open Access

    Translating insights into tumor evolution to clinical practice: promises and challenges

    Accelerating technological advances have allowed the widespread genomic profiling of tumors. As yet, however, the vast catalogues of mutations that have been identified have made only a modest impact on clinic...

    Matthew W. Fittall, Peter Van Loo in Genome Medicine (2019)

  3. Article

    Open Access

    Recurrent rearrangements of FOS and FOSB define osteoblastoma

    The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FO...

    Matthew W. Fittall, William Mifsud, Nischalan Pillay, Hongtao Ye in Nature Communications (2018)

  4. No Access

    Article

    Left ventricular pacing should be considered when biventricular pacing worsens heart failure: left ventricular pacing instead of biventricular pacing?

    Syed Y. Ahsan, Matthew W. Fittall in Journal of Interventional Cardiac Electrop… (2012)