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Article
Open AccessLearning representations for image-based profiling of perturbations
Measuring the phenotypic effect of treatments on cells through imaging assays is an efficient and powerful way of studying cell biology, and requires computational methods for transforming images into quantita...
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Article
Open AccessPolarization properties and Umov effect of human hair
This study delves into the polarization properties of various hair colors using several techniques, including polarization ray tracing, full Stokes, and Mueller matrix imaging. Our analysis involved studying h...
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Article
Open AccessGenetic stabilization of attenuated oral vaccines against poliovirus types 1 and 3
Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus, OPV evolves rapidly t...
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Open AccessEvaluating the policy of closing bars and restaurants in Cataluña and its effects on mobility and COVID19 incidence
The world has gone through unprecedented changes since the global pandemic hit. During the early phase of the pandemic, the absence of known drugs or pharmaceutical treatments forced governments to introduce d...
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Article
Open AccessCOVID-19 Flow-Maps an open geographic information system on COVID-19 and human mobility for Spain
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which has spread all over the world leading to a global pandemic. The fast progression of COVID-19 has been mainly related to the high contagio...
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Article
Open AccessBehavioral responses to a cyber attack in a hospital environment
Technical and organizational steps are necessary to mitigate cyber threats and reduce risks. Human behavior is the last line of defense for many hospitals and is considered as equally important as technical se...
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Article
Open AccessThe scaling of social interactions across animal species
Social animals self-organise to create groups to increase protection against predators and productivity. One-to-one interactions are the building blocks of these emergent social structures and may correspond t...
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Article
Open AccessSilencing miR-370-3p rescues funny current and sinus node function in heart failure
Bradyarrhythmias are an important cause of mortality in heart failure and previous studies indicate a mechanistic role for electrical remodelling of the key pacemaking ion channel HCN4 in this process. Here we...
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Open AccessStroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma
Although immune checkpoint inhibitors (ICIs) have achieved unprecedented results in melanoma, the biological features of the durable responses initiated by these drugs remain unknown. Here we show the genetic ...
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Article
Open AccessAblation-resistant carbide Zr0.8Ti0.2C0.74B0.26 for oxidizing environments up to 3,000 °C
Ultra-high temperature ceramics are desirable for applications in the hypersonic vehicle, rockets, re-entry spacecraft and defence sectors, but few materials can currently satisfy the associated high temperatu...
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Article
Open AccessA fine balance: individualism, society and the prevention of mental illness in the United States, 1945–1968
In the introduction to a collection of his essays entitled Society as Patient (1950), American social scientist and Rockefeller Foundation administrator Lawrence K Frank (1890–1968) claimed that, to prevent th...
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Nutrition: Fall in fish catch threatens human health
Christopher Golden and colleagues calculate that declining numbers of marine fish will spell more malnutrition in many develo** nations.
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Open AccessInterface engineering of graphene for universal applications as both anode and cathode in organic photovoltaics
The high transparency of graphene, together with its good electrical conductivity and mechanical robustness, enable its use as transparent electrodes in optoelectronic devices such as solar cells. While initia...