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  1. No Access

    Article

    FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells

    Screening of cells transduced with a lentivirus library harboring nucleosome-free regions of mammalian genomes identifies cis elements that regulate transcription.

    Matthew Murtha, Zeynep Tokcaer-Keskin, Zuojian Tang, Francesco Strino… in Nature Methods (2014)

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    Protocol

    Isolation and Analysis of DNA Derived from Nucleosome-Free Regions

    Precise regulation of the levels and timing of gene expression is fundamental to all biological processes and is largely determined by the activity of cis-regulatory modules, containing the binding sites for tran...

    Matthew Murtha, Yatong Wang, Claudio Basilico, Lisa Dailey in Gene Regulation (2013)