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  1. Article

    Open Access

    Lower limb muscle strength and balance in older adults with a distal radius fracture: a systematic review

    Distal radius fractures are common fractures in older adults and associated with increased risk of future functional decline and hip fracture. Whether lower limb muscle strength and balance are impaired in thi...

    Colin Forde, Philippa JA Nicolson, Charlotte Vye in BMC Musculoskeletal Disorders (2023)

  2. Article

    Open Access

    Physiotherapy Rehabilitation Post Patellar Dislocation (PRePPeD)—protocol for an external pilot randomised controlled trial and qualitative study comparing supervised versus self-managed rehabilitation for people after acute patellar dislocation

    Patellar dislocations mainly affect adolescents and young adults. After this injury, patients are usually referred to physiotherapy for exercise-based rehabilitation. Currently, limited high-quality evidence e...

    Colin Forde, Matthew L. Costa, Jonathan A. Cook in Pilot and Feasibility Studies (2023)

  3. Article

    Open Access

    Group sequential designs in pragmatic trials: feasibility and assessment of utility using data from a number of recent surgical RCTs

    Assessing the long term effects of many surgical interventions tested in pragmatic RCTs may require extended periods of participant follow-up to assess effectiveness and use patient-reported outcomes that requ...

    Nick R. Parsons, Nigel Stallard, Helen Parsons in BMC Medical Research Methodology (2022)

  4. Article

    Open Access

    Flexibility and resistance exercises versus usual care for improving pain and function after distal radius fracture in adults aged 50 years or over: protocol for the WISE randomised multicentre feasibility trial

    Distal radius fractures represent about 1 in 5 of all fractures treated in UK hospitals. Most distal radius fractures occur in women aged 50 years or over after a fall. Distal radius fractures are managed usin...

    David J. Keene, Cynthia Srikesavan, Juul Achten in Pilot and Feasibility Studies (2022)

  5. Article

    Open Access

    Correction to: Reamed intramedullary nailing versus circular frame external fixation for segmental tibial fractures (STIFF-F): a mixed methods feasibility study

    Caroline B. Hing, Elizabeth Tutton, Toby O. Smith in Pilot and Feasibility Studies (2021)

  6. Article

    Open Access

    Reamed intramedullary nailing versus circular frame external fixation for segmental tibial fractures (STIFF-F): a mixed methods feasibility study

    Segmental tibial fractures are fractures in two or more areas of the tibial diaphysis resulting in a separate intercalary segment of the bone. Surgical fixation is recommended for patients with segmental tibia...

    Caroline B. Hing, Elizabeth Tutton, Toby O. Smith in Pilot and Feasibility Studies (2021)

  7. Article

    Open Access

    Monitoring activity of hip injury patients (MoHIP): a sub-study of the World Hip Trauma Evaluation observational cohort study

    Hip fracture is common, affecting 20% of women and 10% of men during their lifetime. The trajectory of patients’ recovery as they transition from the acute hospital setting to their usual residence is poorly u...

    Laura C. Armitage, Yuan Chi, Mauro Santos, Beth K. Lawson in Pilot and Feasibility Studies (2020)

  8. Article

    Open Access

    Cast versus functional brace in the rehabilitation of patients with a rupture of the Achilles tendon: statistical analysis plan for the UK study of tendo Achilles rehabilitation (UK STAR) multi-centre randomised controlled trial

    The incidence of Achilles tendon rupture in the UK is increasing and the best rehabilitation strategy for patients treated non-operatively remains unclear. We describe a statistical analysis plan (SAP) for the...

    Ioana R. Marian, Matthew L. Costa, Susan J. Dutton in Trials (2019)

  9. Article

    Open Access

    Total hip arthroplasty versus hemiarthroplasty for independently mobile older adults with intracapsular hip fractures

    Displaced intracapsular hip fractures are typically treated with hemiarthroplasty (HA) or total hip arthroplasty (THA). A number of professional bodies recommend considering THA for patients that were independ...

    David Metcalfe, Andrew Judge, Daniel C. Perry in BMC Musculoskeletal Disorders (2019)

  10. Article

    Open Access

    Wound Healing In Surgery for Trauma (WHIST): statistical analysis plan for a randomised controlled trial comparing standard wound management with negative pressure wound therapy

    In the context of major trauma, the rate of wound infection in surgical incisions created during fracture fixation amongst patients with closed high-energy injuries is high. One of the factors which may reduce...

    Ruth Knight, Louise M. Spoors, Matthew L. Costa, Susan J. Dutton in Trials (2019)

  11. Article

    Open Access

    Participation in a trial in the emergency situation: a qualitative study of patient experience in the UK WOLLF trial

    Patients can struggle to make sense of trials in emergency situations. This study examines patient experience of participating in the United Kingdom, Wound management of Open Lower Limb Fractures (UK WOLLF) st...

    Elizabeth Tutton, Juul Achten, Sarah E. Lamb, Keith Willett, Matthew L. Costa in Trials (2018)

  12. Article

    Open Access

    Trial of Acute Femoral Fracture Fixation (TrAFFix): study protocol for a randomised controlled feasibility trial

    Distal femoral fractures are a source of considerable morbidity and best treatment is currently uncertain. The Trial of Acute Femoral Fracture Fixation (TrAFFix) is a randomised, parallel-group feasibility stu...

    Xavier L. Griffin, Matthew L. Costa, Juul Achten, Melina Dritsaki, Janis Baird in Trials (2017)

  13. No Access

    Article

    Is meniscal allograft transplantation chondroprotective? A systematic review of radiological outcomes

    The primary aim of this systematic review was to examine the hypothesis that meniscal allograft transplantation is chondroprotective by identifying and appraising studies that have assessed the progression of ...

    Nick A. Smith, Benjamin Parkinson in Knee Surgery, Sports Traumatology, Arthros… (2016)

  14. Article

    Open Access

    Biomarkers of early stage osteoarthritis, rheumatoid arthritis and musculoskeletal health

    There is currently no biochemical test for detection of early-stage osteoarthritis (eOA). Tests for early-stage rheumatoid arthritis (eRA) such as rheumatoid factor (RF) and anti–cyclic citrullinated peptide (...

    Usman Ahmed, Attia Anwar, Richard S. Savage, Matthew L. Costa in Scientific Reports (2015)

  15. No Access

    Article

    Theatre within 36 h for patients with fracture of the proximal femur: can we deliver?

    Proximal femur fractures carry significant levels of morbidity and mortality. Surgical delay is one factor that adversely affects outcome in these patients. In 2010, hospital-income from patients with proximal...

    Christopher E. Hill, Iestyn M. Shapey in Archives of Orthopaedic and Trauma Surgery (2013)

  16. Article

    Open Access

    An evaluation of the quality of statistical design and analysis of published medical research: results from a systematic survey of general orthopaedic journals

    The application of statistics in reported research in trauma and orthopaedic surgery has become ever more important and complex. Despite the extensive use of statistical analysis, it is still a subject which i...

    Nick R Parsons, Charlotte L Price, Richard Hiskens in BMC Medical Research Methodology (2012)

  17. Article

    Open Access

    The Achilles tendon total rupture score: a study of responsiveness, internal consistency and convergent validity on patients with acute Achilles tendon ruptures

    The Achilles tendon Total Rupture Score was developed by a research group in 2007 in response to the need for a patient reported outcome measure for this patient population. Beyond this original development pa...

    Rebecca S Kearney, Juul Achten, Sarah E Lamb in Health and Quality of Life Outcomes (2012)

  18. Article

    Open Access

    UK DRAFFT - A randomised controlled trial of percutaneous fixation with kirschner wires versus volar locking-plate fixation in the treatment of adult patients with a dorsally displaced fracture of the distal radius

    Fractures of the distal radius are extremely common injuries in adults. However, the optimal management remains controversial. In general, fractures of the distal radius are treated non-operatively if the bone...

    Matthew L Costa, Juul Achten, Nick R Parsons, Amar Rangan in BMC Musculoskeletal Disorders (2011)

  19. Article

    Open Access

    The comprehensive cohort model in a pilot trial in orthopaedic trauma

    The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using ac...

    Rebecca S Kearney, Juul Achten, Nick R Parsons in BMC Medical Research Methodology (2011)

  20. Article

    Open Access

    Warwick Hip Trauma Study: a randomised clinical trial comparing interventions to improve outcomes in internally fixed intracapsular fractures of the proximal femur. Protocol for The WHiT Study

    Controversy exists regarding the optimal treatment for patients with displaced intracapsular fractures of the proximal femur. The recognised treatment alternatives are arthroplasty and internal fixation. The p...

    Xavier Luke Griffin, Nick Parsons, Juul Achten in BMC Musculoskeletal Disorders (2010)

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