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  1. No Access

    Article

    MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer

    Recent publications have shown patients with defects in the DNA mismatch repair (MMR) pathway driven by either MSH2 or MSH6 loss experience a significant increase in the incidence of prostate cancer. Moreover,...

    Patrick McCoy, Stefano Mangiola, Geoff Macintyre… in Prostate Cancer and Prostatic Diseases (2021)

  2. No Access

    Article

    Percutaneous image-guided biopsy of prostate cancer metastases yields samples suitable for genomics and personalised oncology

    Personalised oncology through mutational profiling of cancers requires the procurement of fresh frozen tumour samples for genomics applications. While primary cancers are often surgically excised and therefore...

    Matthew K. H. Hong, Nikhil Sapre, Pramit M. Phal… in Clinical & Experimental Metastasis (2014)