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32 Result(s)
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Article
GLP-1-ra and heart failure-related outcomes in patients with and without history of heart failure: an updated systematic review and meta-analysis
Glucagon-like peptide-1 receptor agonists (GLP1-ra) have shown to reduce cardiovascular (CV) events in patients with diabetes, including heart failure (HF) hospitalizations. However, whether such benefit consi...
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Article
Double mutation in genes associated to FH and diabetes
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Book and Reference Work
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Reference Work Entry In depth
Gut Microbiota and Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is characterized by poor insulin secretion from pancreatic beta cells together with reduced insulin sensitivity of adipose tissue, liver, and muscle. This results in an improper...
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Article
Open AccessGLP-1RAs and cardiovascular disease: is the endothelium a relevant platform?
Hyperglycemia strongly affects endothelial function and activation, which in turn increases the risk of atherosclerotic cardiovascular disease. Among pharmacotherapies aimed at lowering blood glucose levels, g...
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Article
Correction: The visceral adipose tissue bacterial microbiota provides a signature of obesity based on inferred metagenomic functions
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Article
The visceral adipose tissue bacterial microbiota provides a signature of obesity based on inferred metagenomic functions
Metabolic inflammation mediated obesity requires bacterial molecules to trigger immune and adipose cells leading to inflammation and adipose depot development. In addition to the well-established gut microbiot...
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Article
Open AccessMicrobiota-gut-brain axis: relationships among the vagus nerve, gut microbiota, obesity, and diabetes
The purpose of this review is to explore the interconnected pathways of the microbiota-gut-brain axis (MGBA), focusing on the roles of the vagus nerve and glucagon like peptide-1 in appetite control, and in th...
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Article
Open AccessSafety of metformin continuation in diabetic patients undergoing invasive coronary angiography: the NO-STOP single arm trial
Despite paucity of data, it is common practice to discontinue metformin before invasive coronary angiography due to an alleged risk of Metformin-Associated Lactic Acidosis (M-ALA). We aimed at assessing the sa...
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Book and Living Reference Work (Continuously updated edition)
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Living Reference Work Entry In depth
Gut Microbiota and Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is characterized by poor insulin secretion from pancreatic beta cells together with reduced insulin sensitivity of adipose tissue, liver, and muscle. This results in an improper...
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Article
Open AccessImpact of light therapy on rotating night shift workers: the EuRhythDia study
Disturbances in circadian rhythms may promote cardiometabolic disorders in rotating night shift workers (r-NSWs). We hypothesized that timed light therapy might reverse disrupted circadian rhythms and glucose ...
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Article
Open AccessTIMP3 involvement and potentiality in the diagnosis, prognosis and treatment of diabetic nephropathy
Diabetic kidney disease, one of the most severe complications associated with diabetes, is characterized by albuminuria, glomerulosclerosis and progressive loss of renal function. Loss of TIMP3, an Extracellul...
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Article
Open AccessAlterations in Rev-ERBα/BMAL1 ratio and glycated hemoglobin in rotating shift workers: the EuRhythDia study
To detect premature gluco-metabolic defects among night shift workers with disturbances in circadian rhythms.
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Article
Open AccessThe risk of carotid plaque instability in patients with metabolic syndrome is higher in women with hypertriglyceridemia
Metabolic syndrome certainly favors growth of carotid plaque; however, it is uncertain if it determines plaque destabilization. Furthermore, it is likely that only some components of metabolic syndrome are ass...
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Article
Venous distal bypass should be considered as the gold standard to finally attempt limb salvage in patients with severe critical limb ischemia and diabetic foot, or under dialysis
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Article
Timp3 deficiency affects the progression of DEN-related hepatocellular carcinoma during diet-induced obesity in mice
Obesity and low-grade inflammation are associated with an increased risk of hepatocellular carcinoma (HCC), a leading cause of cancer-related death worldwide. The tissue inhibitor of metalloproteinase (TIMP) 3...
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Article
Consider the microbiome in the equation! They were here before us...and hosted us!
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Article
Gut microbiome and cardiometabolic risk
The last decade has been characterized by an intense research on the composition of the gut microbiome and the links with human health. While previous work was focused on the effects of prebiotics and probioti...
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Article
Our second genome and the impact on metabolic disorders: why gut microbiome is an important player in diabetes and associated abnormalities
