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Article
Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer
The present study investigated the expression and role of ROR2 in small cell lung cancer (SCLC). To examine the expression of ROR2, 27 surgically resected SCLC tissue samples were immunostained for ROR2. Sixte...
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Article
Open AccessSIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice
Brown adipose tissue plays a central role in the regulation of the energy balance by expending energy to produce heat. NAD+-dependent deacylase sirtuins have widely been recognized as positive regulators of brown...
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Article
Open AccessGenome editing using a versatile vector-based CRISPR/Cas9 system in Fusarium species
Fusarium species include important filamentous fungal pathogens that can infect plants, animals, and humans. Meanwhile, some nonpathogenic Fusarium species are promising biocontrol agents against plant pathogens....
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Chapter and Conference Paper
Finger-Touch Direction Feature Using a Frequency Distribution in the Writer Verification Base on Finger-Writing of a Simple Symbol
In this study, individuals were asked to draw a symbol by using their fingertips on a digital device screen. This study focused on finger-touch direction information that can be extracted from a smartphone scr...
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Article
Open AccessThree-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments
Colorectal cancer demonstrates intra-tumour heterogeneity formed by a hierarchical structure comprised of cancer stem cells (CSCs) and their differentiated progenies. The mechanism by which CSCs are maintained...
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Article
ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a transcriptional target of the lineage-survival oncogene NKX2–1/TTF-1 in lung adenocarcinomas. In addition to its kinase-dependent role, ROR1 func...
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Article
Sliding Dynamics of the Wigner Crystal on Liquid He
The Wigner crystal on liquid He accompanies with periodic corrugation of the He surface; dimples. The dynamics of the crystal is coupled with the motion and the deformation of the dimples. Nonlinear phenomena ...
