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Article
Open AccessChanges in HER3 expression profiles between primary and recurrent gynecological cancers
Human epidermal growth factor receptor-3 (HER3) is a member of the epidermal growth factor receptor family of receptor tyrosine kinases, and its overexpression is associated with inferior prognosis in several ...
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Article
Open AccessHigh mesothelin expression is correlated with non-squamous cell histology and poor survival in cervical cancer: a retrospective study
Mesothelin (MSLN) is a cell-surface glycoprotein found in various solid tumours. Cancer therapies targeting MSLN have been developed in recent years; however, the available information on MSLN expression in ce...
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Article
Microcystic stromal tumor of the ovary: a recurrent case with somatic CTNNB1 missense mutation
Microcystic stromal tumors (MCSTs) of the ovary are rare sex cord-stromal tumors that are considered benign neoplasms because almost all cases display unilateral, localized lesions and have benign outcomes, ex...
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Article
Genetic features of endometrioid-type endometrial carcinoma arising in uterine adenomyosis
This study aimed to clarify the genetic features of endometrioid-type endometrial cancer arising in adenomyosis (EC-AIA) using targeted sequencing and immunohistochemistry (IHC) for both carcinoma and adjacent...
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Article
Gastric-type cervical adenocarcinoma with squamous differentiation: buried in adenosquamous carcinomas?
Gastric-type adenocarcinoma (GAS) of the cervix is a human papilloma virus (HPV)–independent, aggressive, and chemo-resistant adenocarcinoma. However, although the histopathological features of GAS have been e...
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Article
Lymphopenia after induction chemotherapy correlates with incomplete surgical resection in patients with advanced ovarian cancer
Lymphopenia is associated with poor outcomes in patients with various cancers, but little is known about the prognostic impact of lymphopenia in patients with epithelial ovarian cancer (EOC) after induction ch...
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Article
Open AccessA case of mature cystic teratoma with intestinal structures harboring intestinal-type low-grade mucinous neoplasm
The formation of gastrointestinal-type epithelium is found in 7–13% of mature cystic teratomas, which are the most common germ cell tumors of the ovary. Few cases harboring organized gastrointestinal tract for...
