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Article
Open AccessEvolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif
The interactions between PDZ (PSD-95, Dlg, ZO-1) domains and PDZ-binding motifs play central roles in signal transductions within cells. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively ...
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Corticotropin-Releasing Factor (CRF) and its Role in the Central Nervous System
Corticotropin-releasing factor, commonly termed CRF, was originally described as a neurohumoral factor in the hypothalamus-pituitary system that regulates the synthesis and secretion of adrenocorticotropic hor...