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Article
Open AccessBronchioalveolar stem cells derived from mouse-induced pluripotent stem cells promote airway epithelium regeneration
Bronchioalveolar stem cells (BASCs) located at the bronchioalveolar-duct junction (BADJ) are stem cells residing in alveoli and terminal bronchioles that can self-renew and differentiate into alveolar type (AT...
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Article
Prophylactic administration of granulocyte colony-stimulating factor in epirubicin and cyclophosphamide chemotherapy for Japanese breast cancer patients: a retrospective study
Epirubicin and cyclophosphamide (EC) therapy, a major chemotherapy for patients with early-stage breast cancer, has a low risk (< 10%) of febrile neutropenia (FN). However, data used in reports on the incidenc...
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Chapter
Methodology: CT Lymphography
Sentinel lymph node (SLN) navigation surgery became the routine clinical procedure in breast cancer (BC) surgery. SLN navigation has also been introduced to gastrointestinal cancer but still remains controvers...
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Chapter
Molecular Diagnosis and Targeting Therapy for Breast Cancer
Breast cancer (BC) is a representative cancer for which molecular targeting therapy is most popular, because systemic therapy is selected according to tumor biological subtypes, luminal A, luminal B, HER2-enri...
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Article
A randomized, open label study of the efficacy of prophylactic 24-h low-dose landiolol for atrial fibrillation in transthoracic esophagectomy
Atrial fibrillation (Af) is one of the common cardiovascular complications after esophagectomy. Low-dose landiolol prevented postoperative Af after administration was previously reported. We evaluated the prev...
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Article
Immunocytochemical results for HER2 and Ki67 in breast cancer touch-smear cell specimens are reliable
Re-evaluation of the subtype of recurrent breast cancer is necessary for deciding the treatment approach, but it is often not performed due to the difficulty of obtaining tissue specimens from a recurrent lesi...
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Article
Preoperative diagnosis of sentinel lymph node (SLN) metastasis using 3D CT lymphography (CTLG)
Sentinel lymph node biopsy (SLNB) became a standard procedure for patients with early breast cancer, however, an indication of SLN navigation to metastatic disease may lead to misdiagnosis for staging. Preoper...
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Article
Triple assessment of sentinel lymph node metastasis in early breast cancer using preoperative CTLG, intraoperative fluorescence navigation and OSNA
Sentinel lymph node biopsy (SLNB) became a standard surgical procedure for patients with early breast cancer; however, the optimal method of sentinel lymph node (SLN) identification remains controversial. The...
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Article
Long-term survival for advanced esophageal cancer patients with an esophago-bronchial fistula can be achieved by timely multimodality therapy
We reported four consecutive advanced esophageal cancer patients with esophago-bronchial fistula (EBF) who were managed well and achieved long-term survival with timely multimodality therapy including bypass o...
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Article
Open AccessThe time since last menstrual period is important as a clinical predictor for non-steroidal aromatase inhibitor-related arthralgia
The clinical predictors of aromatase inhibitor-related arthralgia (AIA), a drug-related adverse reaction of aromatase inhibitors (AIs), remain unclear.
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Article
Aberrant retrotracheal goiter: Report of a case
A case of intrathoracic retrotracheal goiter in a 40-year-old woman is herein described. A computed tomographic scan, magnetic resonance imaging and endoscopical ultrasonography all confirmed the existence of ...
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Article
Rare variants of Hodgkin's disease of the thymus: Report of two cases and proposal for effective clinical management
We treated two patients with rare variants of Hodgkin's disease of the thymus. One was a 17-year-old girl with a thymoma-like shadow on the chest X-rays, an increased erythrocyte sedimentation rate and an elev...
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Article
Scintiscanning demonstration of thymoma: Comparative study on scintiscans using201Tl,67Ga and75Se
Thymus scintigraphy was performed using201Tl-chloride,67-Ga-citrate and75Se-selenomethionine on 30 thymoma patients with or without myasthenia gravis. Mass negativity was observed in 6 out of 17 (35.3 per cent) a...
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Article
Somatic and psychomotor development of children after hypothermic open-heart surgery
One hundred and seven patients with ventricular septal defect who survived one and a half to thirteen years after hypothermic open-heart surgery were reviewed with respect to somatic, intellectual, and psychom...
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Article
Inhibitory mechanisms of insulin secretion associated with hyothermic open-heart surgery
In order to clarify the inhibitory mechanism of insulin secretion associated with open-heart surgery, the influence of insulin antagonistic hormones on insulin secretion was studied in 20 patients with congeni...
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Article
Studies of lipid and carbohydrate metabolism during surface-induced deep hypothermia with circulatory arrest for open-heart surgery
Plasma lipids, blood glucose, plasma insulin (IRI) and serum dopamine-β-hydroxylase (DBH) were measured in 30 subjects undergoing surface-induced deep hypothermia with circulatory arrest for open-heart surgery...
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Article
The role of the liver in the changes of acid-base balance and plasma lipids during surface-induced deep hypothermia
The role of the liver in the changes of acid-base balance and plasma lipids in surface-induced deep hypothermia for open-heart surgery was investigated clinically and experimentally. The metabolic acidosis gen...
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Article
Metabolic changes in surface-induced deep hypothermia combined with cardiopulmonary bypass for cardiac surgery
Surface induced deep hypothermia combined with cardiopulmonary bypass (combined method) is excellent in open heart surgery of infants which combines each advantage of cardiopulmonary bypass and hypothermia. Th...
