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Article
Macrophage requirements for mouse B-cell stimulation differ according to the molecular form of anti-IgM antibodies
THYMUS-INDEPENDENT lymphocytes (B cells) comprise a heterogeneous population. Because of this heterogeneity, the precise nature of the signals which activate resting B cells to become antibody-forming cells is...
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Chapter and Conference Paper
A Single Recessive Non-MHC Diabetogenic Gene Determines the Development of Insulitis in NOD Mice
Insulin-dependent diabetes of man, the BB rat and the NOD mouse appears to result from autoimmune β cell destruction in a setting of genetic predisposition. The NOD mouse develops insulin-dependent diabetes se...
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Chapter and Conference Paper
Type-I (insulin-dependent) and type-II (non-insulin-dependent) diabetes mellitus in BC1[(NODxMus spretus)F1xNOD] mice
The nonobese diabetic (NOD), nonobese nondiabetic (NON), cataract Shionogi (CTS), ICR-L-Ishibe (ILI) and ICR-I-Ishibe (III) mouse strains have been used in our experiments. The NOD, NON, CTS and ILI mice were ...
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Chapter
Occurrence of pretype I diabetes (pre-IDDM) and type II diabetes (NIDDM) in BC1 [(NOD x Mus spretus) F1 x NOD] mice
Type I human diabetes (IDDM), the BB rat, and the NOD mouse appear to result from autoimmune B-cell destruction in a setting of genetic predisposition.1,2 The NOD/Shi mouse was established in 1980 at the Shionogi...
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Article
Long-term follow up of patients with multiple gastric carcinoids associated with type A gastritis
Little is known about the natural course of multiple gastric carcinoids associated with type A gastritis. Between 1993 and 2003, we enrolled eight patients, diagnosed as having multiple gastric carcinoids asso...
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Article
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
Inactivation of TGF-β family signaling is implicated in colorectal tumor progression. Using cis-Apc+/Δ716 Smad4+/− mutant mice (referred to as cis-Apc/Smad4), a model of invasive colorectal cancer in which TGF-β ...
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Article
Laparoscopic Surgery for the Ascending Colon Cancer Associated with Malrotation of the Midgut
Malrotation of the midgut is a congenital anomaly of the gastrointestinal tract that usually presents in neonates. Moreover, synchronous colon cancer has rarely been reported. In the present article, we report...
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Article
Single-Incision Laparoscopic Ileo-Cecal Resection for Appendiceal Mucocele
Mucocele of the appendix is a rare lesion which denotes a distension of the lumen due to accumulation of mucoid substance, and a possible rupture of the mucocele may result in the clinical condition of pseudom...
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Article
The Transverse Colon Cancer with the Reversed Rotation of the Midgut Treated with Single Incision Laparoscopic Colectomy
Reversed rotation of the midgut is a rare type of intestinal malrotation. Moreover, synchronous colon cancer has rarely been reported. Preliminary experience with single-incision laparoscopic colectomy (SILC) ...
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Article
Single Incision Laparoscopic Right Colectomy Using the Techniques of Open Surgery Through the Small Incision
To perform single-incision laparoscopic colectomy (SILC) safely while maintaining the minimal invasiveness of SILC and the quality of the lymph node dissection, we have used hybrid single-incision laparoscopic...
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Article
Concurrent Single-Incision Laparoscopic Right Hemicolectomy and Sigmoidectomy for Synchronous Carcinoma: Report of a Case
Synchronous colorectal tumors that require surgical treatments are rare. Preliminary experience with concurrent single-incision laparoscopic right hemicolectomy and sigmoidectomy for synchronous carcinoma is r...
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Article
Single-Incision Laparoscopic Surgery for Colon Cancer in Patient with Situs Inversus Totalis: Report of a Case
A preliminary experience with single-incision laparoscopic colectomy for colon cancer with situs inversus totalis (SIT) is reported. An 87-year-old man was admitted because of a fecal occult blood. A colonosco...
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Article
A New Laparoscopic Rectal Transection Method via Umbilical Incision Using Endo GIA™ Radial Reload
We have developed a new laparoscopic rectal transection method via umbilical incision using Endo GIA™ Radial Reload with a Tri-Staple™ Technology (RR) (Covidien, New Haven, CT) stapler. A 65-year-old woman wit...
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Article
The Use of the EndoGrab™ Port-Free Endocavity Retractor in Single-Incision Laparoscopic Right Hemicolectomy
The EndoGrab™ Port-Free Endocavity Retractor is an internally anchored retracting device that enables surgeons to reduce not only the number of ports and incisions but also the number of assistant surgeons. Ou...
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Article
Open AccessSerum uric acid is an independent predictor of new-onset diabetes after living-donor kidney transplantation
We investigated whether serum uric acid (SUA) levels before kidney transplantation predict new-onset diabetes after kidney transplantation (NODAT) and compared SUA levels with known risk factors for NODAT by p...
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Article
Open AccessThe impact of senescence-associated T cells on immunosenescence and age-related disorders
Immunosenescence is age-associated changes in the immunological functions, including diminished acquired immunity against infection, pro-inflammatory traits, and increased risk of autoimmunity. The proportions...
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Article
Single-Incision Laparoscopic Colectomy for Descending Colon Cancer: a Single Institutional Experience
The applicability of single-incision laparoscopic colectomy (SILC) for descending colon cancer is poorly understood. In the present study, consecutive experiences with SILC for descending colon cancer are revi...
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Article
Open AccessA case of portal venous gas after obstructive transverse colon cancer surgery
Portal venous gas has traditionally been considered an inevitable harbinger of death due to its association with bowel necrosis. Recently, an increasing number of cases of portal venous gas have been reported ...
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Article
Open AccessAnorectal injury related to a personal watercraft: a case report and literature review
Douche injury is a rare consequence of water recreation activities. Generally, this type of trauma occurs when people fall into the water in a sitting position during high-speed activities such as using a pers...
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Article
Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity
Among several mechanisms for the resistance of human epidermal growth factor receptor 2-overexpressing (HER2 +) cancer cells to trastuzumab, little is known regarding the mechanism underlying the resistance to...
