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  1. Article

    Open Access

    Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model

    Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by a selective loss of upper and lower motor neurons. Recent studies have shown that mutations in SQSTM1 are linked to ...

    Shun Mitsui, Asako Otomo, Masahisa Nozaki, Suzuka Ono, Kai Sato in Molecular Brain (2018)