4 Result(s)
within
Masahiro Uesaka
Paleontology
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Article
Open AccessHagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences
Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes genome architecture and is often assumed to be causally associated with organismal innovations and radiations. The 2R hyp...
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Article
Open AccessRecapitulation-like developmental transitions of chromatin accessibility in vertebrates
The relationship between development and evolution has been a central theme in evolutionary developmental biology. Across the vertebrates, the most highly conserved gene expression profiles are found at mid-em...
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Article
Open AccessEmbryonic lethality is not sufficient to explain hourglass-like conservation of vertebrate embryos
Understanding the general trends in developmental changes during animal evolution, which are often associated with morphological diversification, has long been a central issue in evolutionary developmental bio...
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Article
Constrained vertebrate evolution by pleiotropic genes
Despite morphological diversification of chordates over 550 million years of evolution, their shared basic anatomical pattern (or ‘bodyplan’) remains conserved by unknown mechanisms. The developmental hourglas...
