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Article
Accumulation and Phagocytosis of Fluorescently Visualized Macrophages Against Edwardsiella piscicida Infection in Established mpeg1.1-Transgenic Japanese Medaka Oryzias latipes
Intracellular bacteria such as those belonging to the genus Edwardsiella can survive and proliferate within macrophages. However, the detailed mechanisms underlying the host macrophage immune response and pathoge...
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Article
Open AccessComparison of therapeutic strategies for aortic stenosis between transcatheter and surgical aortic valve implantation: a retrospective cohort study in Japanese dialysis patients
Although transcatheter aortic valve implantation (TAVI) is assumed to be a less invasive therapy in high-risk patients with aortic valve stenosis (AS), there have been limited data suggesting its beneficial ef...
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Article
Transcriptomic analysis of cultured kuruma shrimp primary lymphoid organ cells for identifying key cascades hindering sustainable culture
The progress of virology research in shrimp has been hampered by a lack of immortalized shrimp cell lines, and even long-term and stable primary cell cultures have not been perfectly achieved. Here, transcript...
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Article
Open AccessImpact of early initiation of renin-angiotensin blockade on renal function and clinical outcomes in patients with hypertensive emergency: a retrospective cohort study
Hypertensive emergency is a critical disease that causes multifaceted sequelae, including end-stage kidney disease and cardiovascular disease. Although the renin–angiotensin–aldosterone (RAA) system is enormou...
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Wave Radar Application to the Simplified Parametric Roll Operational Guidance at Actual Sea
The authors executed measurements of the encounter waves by an X band wave radar and the roll angles by a gyro sensor onboard for a Ropax ship. By using the measured wave spectrum, the roll amplitude is estima...
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Article
Practical method for evaluating wind influence on autonomous ship operations
The autonomous operations of marine vehicles have recently attracted significant attention. In particular, automation of harbor operations, such as autonomous docking or berthing, is a challenging target. In l...
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Article
Theoretical estimation of joint probability density function of roll angle and angular acceleration in beam seas using PDF line integral method
So far, we have developed a calculation method for roll angular acceleration and its derivative, which is a jerk. In this study, using the probability density function (PDF) line integral method and the joint ...
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Article
Theoretical determination of roll angular jerk of ships in irregular beam seas using PDF line integral method
The time derivative of acceleration is called a jerk, which is an important property to evaluate ride comfort in elevators, cars, and so on. Likewise, evaluation of motion sickness or ride comfort on a vessel ...
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Article
Theoretical determination of asymmetric rolling amplitude in irregular beam seas
A methodology for predicting the probability density function of roll motion for irregular beam seas is developed in the author’s previous research. In this paper, two methods for the prediction of the probabi...
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Article
Theoretical estimation of roll acceleration in beam seas using PDF line integral method
The prevention of excessive roll acceleration is one of the fundamental requirements of an oceangoing vessel at sea. In this paper, aiming at this requirement, we propose a new theoretical method for calculati...
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Article
Open AccessA defective interleukin-17 receptor A1 causes weight loss and intestinal metabolism-related gene downregulation in Japanese medaka, Oryzias latipes
In the intestine, the host must be able to control the gut microbiota and efficiently absorb transiently supplied metabolites, at the risk of enormous infection. In mammals, the inflammatory cytokine interleuk...
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Article
Open AccessEffects of SGLT2 inhibitors on eGFR in type 2 diabetic patients—the role of antidiabetic and antihypertensive medications
Recent randomized trials demonstrating the beneficial effects of sodium-glucose cotransporter 2 inhibitors (SGLT2is) in type 2 diabetes suggest that early reductions in eGFR upon initiation of SGLT2i therapy a...
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Article
Open AccessFish cytokines: current research and applications
Cytokines are low molecular weight glycoproteins involved in the regulation of the immune system, and more than 100 cytokines have hitherto been identified in humans. Cytokines similar to those found in humans...
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Article
Diel Variation in CC Chemokine Gene Expression in the Japanese Pufferfish Takifugu rubripes
CC chemokines are key molecules in the regulation of leukocyte trafficking to the site of injury, infection, or inflammation. In recent years, some mammalian chemokines have been shown to exhibit rhythmic expr...
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Article
Open Access1/f2 spectra of decoherence noise on 75As nuclear spins in bulk GaAs
To identify the decoherence origin, frequency spectra using multiple π-pulses have been extensively studied. However, little has been discussed on how to define the spectral intensities from multiple-echo deca...
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Article
Estimating a non-Gaussian probability density of the rolling motion in irregular beam seas
A methodology for predicting the probability density function of roll motion for irregular beam seas was developed in previous research. That work introduced a non-Gaussian probability density function (PDF), ...
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Article
Open AccessAveraging methods for estimating parametric roll in longitudinal and oblique waves
The International Maritime Organization is still develo** second generation intact stability criteria for the roll motion of ships. For level 2 vulnerability criteria for parametric roll that require no expe...
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Article
On-site Direct Detection of Astaxanthin from Salmon Fillet Using Raman Spectroscopy
A new technology employing Raman spectroscopy is attracting attention as a powerful biochemical technique for the detection of beneficial and functional food nutrients, such as carotenoids and unsaturated fatt...
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Article
Loop-mediated isothermal amplification (LAMP) assays for detection and identification of aquaculture pathogens: current state and perspectives
Since its invention in 2000, loop-mediated isothermal amplification (LAMP) assay has been one of the most extensively used molecular diagnostic tools in bio-medical fields due to the rapidity, accuracy, and co...
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Article
The Wide band p- type material formed by the thin film with ZnO - NiO mixed crystal system
We study ZnO-NiO mixed crystal thin film as a wide band p-type material for the hetero-junction with ZnO. As for the hetero-junction of the ZnO ( n-type ) and the NiO which have relatively stable p-type semicondu...
