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  1. Article

    Open Access

    External validation of the rCAST for patients after in-hospital cardiac arrest: a multicenter retrospective observational study

    No established predictive or risk classification tool exists for the neurological outcomes of post-cardiac arrest syndrome (PCAS) in patients with in-hospital cardiac arrest (IHCA). This study aimed to investi...

    Junki Ishii, Mitsuaki Nishikimi, Kazuya Kikutani, Michihito Kyo in Scientific Reports (2024)

  2. Article

    Open Access

    Comparison of certainty of evidence between the net benefit approach and the traditional GRADE method using the data of Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020

    Takero Terayama, Hiromu Okano, Sadatoshi Kawakami in Journal of Intensive Care (2023)

  3. Article

    Open Access

    Prevalence, reasons, and timing of decisions to withhold/withdraw life-sustaining therapy for out-of-hospital cardiac arrest patients with extracorporeal cardiopulmonary resuscitation

    Extracorporeal cardiopulmonary resuscitation (ECPR) is rapidly becoming a common treatment strategy for patients with refractory cardiac arrest. Despite its benefits, ECPR raises a variety of ethical concerns ...

    Hiromichi Naito, Masaaki Sakuraya, Takashi Hongo, Hiroaki Takada in Critical Care (2023)

  4. Article

    Open Access

    A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study

    Fluid creep, including fluids administered as drug diluents and for the maintenance of catheter patency, is the major source of fluid intake in critically ill patients. Although hypoxemia may lead to fluid res...

    Masaaki Sakuraya, Shodai Yoshihiro, Kazuto Onozuka in Annals of Intensive Care (2022)

  5. Article

    Open Access

    Effects of fentanyl administration in mechanically ventilated patients in the intensive care unit: a systematic review and meta-analysis

    Fentanyl is selected to manage pain in critical care patients on mechanical ventilation in the intensive care unit (ICU). However, the usefulness of fentanyl compared with other opioids is unknown. This study ...

    Yoshitaka Aoki, Hiromi Kato, Naoyuki Fujimura, Yuji Suzuki in BMC Anesthesiology (2022)

  6. Article

    Open Access

    ARDS Clinical Practice Guideline 2021

    The joint committee of the Japanese Society of Intensive Care Medicine/Japanese Respiratory Society/Japanese Society of Respiratory Care Medicine on ARDS Clinical Practice Guideline has created and released th...

    Sadatomo Tasaka, Shinichiro Ohshimo, Muneyuki Takeuchi in Journal of Intensive Care (2022)

  7. Article

    Open Access

    Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan

    The prevalence of extracorporeal cardiopulmonary resuscitation (ECPR) in patients with out-of-hospital cardiac arrest (OHCA) has been increasing rapidly worldwide. However, guidelines or clinical studies do no...

    Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Hiroshi Okamoto in Critical Care (2022)

  8. Article

    Open Access

    Respiratory support strategy in adults with acute hypoxemic respiratory failure: a systematic review and network meta-analysis

    Network meta-analyses (NMAs) of respiratory management strategies for acute hypoxemic respiratory failure (AHRF) have been reported, but no previous study has compared noninvasive ventilation (NIV), high-flow ...

    Hiromu Okano, Masaaki Sakuraya, Tomoyuki Masuyama, Shunsuke Kimata in JA Clinical Reports (2022)

  9. Article

    Open Access

    Accuracy evaluation of mainstream and sidestream end-tidal carbon dioxide monitoring during noninvasive ventilation: a randomized crossover trial (MASCAT-NIV trial)

    The end-tidal partial pressure of carbon dioxide (PETCO2) can be used to estimate the arterial partial pressure of carbon dioxide (PaCO2) in patients who undergo mechanical ventilation via endotracheal intubation...

    Masaaki Sakuraya, Eri Douno, Wakana Iwata, Akihiro Takaba in Journal of Intensive Care (2022)

  10. Article

    Open Access

    Efficacy of non-invasive and invasive respiratory management strategies in adult patients with acute hypoxaemic respiratory failure: a systematic review and network meta-analysis

    Although non-invasive respiratory management strategies have been implemented to avoid intubation, patients with de novo acute hypoxaemic respiratory failure (AHRF) are high risk of treatment failure. In the p...

    Masaaki Sakuraya, Hiromu Okano, Tomoyuki Masuyama, Shunsuke Kimata in Critical Care (2021)

  11. Article

    Open Access

    Clinical prediction scores and early anticoagulation therapy for new-onset atrial fibrillation in critical illness: a post-hoc analysis

    This study sought to describe the epidemiology of anticoagulation therapy for critically ill patients with new-onset atrial fibrillation (NOAF) according to CHA2DS2-VASc and HAS-BLED scores and to assess the e...

    Masaaki Sakuraya, Takuo Yoshida, Yusuke Sasabuchi in BMC Cardiovascular Disorders (2021)

  12. Article

    Open Access

    The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020)

    The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised fr...

    Moritoki Egi, Hiroshi Ogura, Tomoaki Yatabe, Kazuaki Atagi in Journal of Intensive Care (2021)

  13. Article

    Open Access

    Infected thoracoabdominal aortic aneurysm related to an implanted long-term arterial catheter for chemotherapy: a case report

    An infected aortic aneurysm is a rare and life-threatening vascular condition with a high incidence of arterial rupture and recurrence even after treatment. One of the most common causes of an infected aortic ...

    Kiyoshi Takemoto, Michitaka Nakamura, Masaaki Sakuraya in Journal of Medical Case Reports (2021)

  14. Article

    Open Access

    Occurrence and incidence rate of peripheral intravascular catheter-related phlebitis and complications in critically ill patients: a prospective cohort study (AMOR-VENUS study)

    The lack of precise information on the epidemiology of peripheral intravascular catheter (PIVC)-related phlebitis and complications in critically ill patients results in the absence of appropriate preventive m...

    Hideto Yasuda, Ryohei Yamamoto, Yoshiro Hayashi, Yuki Kotani in Journal of Intensive Care (2021)

  15. Article

    Open Access

    The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016)

    The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J-SSCG 2016), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created jointly by th...

    Osamu Nishida, Hiroshi Ogura, Moritoki Egi, Seitaro Fujishima in Journal of Intensive Care (2018)