7 Result(s)
within
Mary N. Sheppard
Cardiology
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Chapter
Mitral Valve Pathology
The mitral valve is composed of leaflets, cords, and papillary muscles which must work in combination for the valve to function properly. The valve leaflets have three distinct layers, the atrialis, the spongi...
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Article
Open AccessNext-generation sequencing using microfluidic PCR enrichment for molecular autopsy
We aimed to determine the mutation yield and clinical applicability of “molecular autopsy” following sudden arrhythmic death syndrome (SADS) by validating and utilizing low-cost high-throughput technologies: F...
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Chapter
The Normal Aorta and Changes with Age
The aorta is the blood vessel responsible for delivering blood from the heart to the systemic circulation. The aortic wall is a highly dynamic and tightly regulated structure that performs sophisticated functi...
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Chapter
Aortic Connective Tissue Histopathology
Aortic disease is a significant cause of death in developed countries. The most common aortic diseases are aneurysm, dissection and atheroma. The microstructure of the aortic medial tissue shows alteration of ...
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Chapter
Genetics and Genomics of Sudden Unexplained Cardiac Death
The aetiology of sudden cardiac death (SCD) and sudden arrhythmic death syndrome (SADS) is not fully explored. Expert cardiac pathology and detailed familial clinical evaluation can identify an inherited cardi...
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Article
Open AccessCalibration of myocardial T2 and T1 against iron concentration
The assessment of myocardial iron using T2* cardiovascular magnetic resonance (CMR) has been validated and calibrated, and is in clinical use. However, there is very limited data assessing the relaxation param...
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Article
Open AccessUltra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque
Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability. The aim of this preliminary study was to show the potential of Ul...
