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Article
Modeling human disease in yeast: recreating the PI3K-PTEN-Akt signaling pathway in Saccharomyces cerevisiae
The yeast Saccharomyces cerevisiae is a model organism that has been thoroughly exploited to understand the universal mechanisms that govern signaling pathways. Due to its ease of manipulation, humanized yeast mo...
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Article
Gaussian mixture models based 2D–3D registration of bone shapes for orthopedic surgery planning
In orthopedic surgery, precise kinematics assessment helps the diagnosis and the planning of the intervention. The correct placement of the prosthetic component in the case of knee replacement is necessary to ...
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Article
Fluoroscopy-based tracking of femoral kinematics with statistical shape models
Precise knee kinematics assessment helps to diagnose knee pathologies and to improve the design of customized prosthetic components. The first step in identifying knee kinematics is to assess the femoral motio...
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Article
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats
The endocannabinoid system is upregulated in both human inflammatory bowel diseases and experimental models of colitis. In this study, we investigated whether this upregulation is a marker also of celiac disea...
