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Article
Open AccessIn vivo analysis of a proprietary glass-based adhesive for sternal fixation and stabilization using rabbit and sheep models
Wire cerclage remains the standard method of care for sternal fixation, following median sternotomy, despite being beset with complications. An emerging treatment option has been to augment the wires with an a...
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Article
The effect of calcination rate on the structure of mesoporous bioactive glasses
Mesoporous bioactive glasses (MBGs) are designed to have high specific surface area. They are formulated by a sol–gel process to formulate the glass followed by calcination. This study evaluates how calcinatio...
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Article
Antibacterial properties of poly (octanediol citrate)/gallium-containing bioglass composite scaffolds
Bioactive glasses may function as antimicrobial delivery systems through the incorporation and subsequent release of therapeutic ions. The aim of this study was to evaluate the antimicrobial properties of a se...
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Article
A glass polyalkenoate cement carrier for bone morphogenetic proteins
This work considers a glass polyalkenoate cement (GPC)-based carrier for the effective delivery of bone morphogenetic proteins (BMPs) at an implantation site. A 0.12 CaO–0.04 SrO–0.36 ZnO–0.48 SiO2 based glass an...
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Article
Fabrication and characterization of poly(octanediol citrate)/gallium-containing bioglass microcomposite scaffolds
Bone can be affected by osteosarcomae requiring surgical excision of the tumor as part of the treatment regime. Complete removal of cancerous cells is difficult and conventionally requires the removal of a mar...
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Article
Investigating the effect of SiO2–TiO2–CaO–Na2O–ZnO bioactive glass doped hydroxyapatite: characterisation and structural evaluation
The effects of increasing bioactive glass additions, SiO2–TiO2–CaO–Na2O–ZnO up to 25 wt% in increments of 5 wt%, on the physical and mechanical properties of hydroxyapatite (HA) sintered at 900, 1000, 1100 and 12...
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Article
Characteristics of glass ionomer cements composed of glass powders in CaO–SrO–ZnO–SiO2 system prepared by two different synthetic routes
Glass ionomer cements (GICs) are composed of an acid degradable glass, polyacrylic acid and water. Sol–gel processing to prepare the glass phase has certain advantages, such as the ability to employ lower synt...
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Article
Develo** Novel Prognostic Biomarkers for Multivariate Fracture Risk Prediction Algorithms
Multivariate prediction algorithms such as FRAX® and QFractureScores provide an opportunity for new prognostic biomarkers to be developed and incorporated, potentially leading to better fracture prediction. As...
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Article
Sol–gel derived silver-incorporated titania thin films on glass: bactericidal and photocatalytic activity
Titanium dioxide (TiO2) and silver-containing TiO2 (Ag-TiO2) thin films were prepared on silica pre-coated float glass substrates by a sol–gel spin coating method. The bactericidal activity of the films was deter...
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Article
Mechanical properties of hydroxyapatite–zirconia compacts sintered by two different sintering methods
Microwave sintering is traditionally employed to reduce the sintering temperature required to densify powder compacts. The effect of microwave heating on hydroxyapatite (HA)–zirconia (ZrO2) green bodies has been ...
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Article
Evaluation of two novel aluminum-free, zinc-based glass polyalkenoate cements as alternatives to PMMA bone cement for use in vertebroplasty and balloon kyphoplasty
Vertebroplasty (VP) and balloon kyphoplasty (BKP) are now widely used for treating patients in whom the pain due to vertebral compression fractures is severe and has proved to be refractory to conservative tre...
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Article
Fabrication of spherical CaO–SrO–ZnO–SiO2 particles by sol–gel processing
This study was concerned with the fabrication of ceramic CaO–SrO–ZnO–SiO2 spherical particles, which are novel candidates for the glass phase in glass polyalkenoate cements (GPCs). GPCs made from these glasses ha...
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Article
The role of Sr2+ on the structure and reactivity of SrO–CaO–ZnO–SiO2 ionomer glasses
The suitability of Glass Polyalkenoate Cements (GPCs) for use in orthopaedics is retarded by the presence in the glass phase of aluminium, a neurotoxin. Unfortunately, the aluminium ion plays an integral role ...
