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  1. Article

    Open Access

    The impact of polydioxanone (PDS) foil thickness on reconstruction of the orbital geometry after isolated orbital floor fractures

    The orbital floor is frequently involved in head trauma. Current evidence on the use of reconstruction materials for orbital floor repair is inconclusive. Accordingly, this study aimed to compare the impact of...

    Philipp Winnand, Mark Ooms, Nassim Ayoub in European Journal of Trauma and Emergency S… (2024)

  2. Article

    Open Access

    Tensile strength of adhesives in peripheral nerve anastomoses: an in vitro biomechanical evaluation of four different neurorrhaphies

    The fundamental prerequisite for prognostically favorable postoperative results of peripheral nerve repair is stable neurorrhaphy without interruption and gap formation.

    Marius Heitzer, Konrad Kilic, Ricarda Merfort in European Journal of Medical Research (2024)

  3. Article

    Open Access

    The role of potassium in depth profiling of the tumor border in bone-invasive oral cancer using laser-induced breakdown spectroscopy (LIBS): a pilot study

    Microscopic tumor spread beyond the macroscopically visible tumor mass in bone represents a major risk in surgical oncology, where the spatial complexity of bony resection margins cannot be countered with rapi...

    Philipp Winnand, K. Olaf Boernsen, Mark Ooms in Journal of Cancer Research and Clinical On… (2023)

  4. Article

    Open Access

    Evaluation of perfusion parameters of gingival inflammation using laser Doppler flowmetry and tissue spectrophotometry– a prospective comparative clinical study

    The aim of this study was to determine the values of different perfusion parameters- such as oxygen saturation, the relative amount of hemoglobin, and blood flow- in healthy subjects compared to patients with ...

    Marie Sophie Katz, Mark Ooms, Philipp Winnand, Marius Heitzer, Anna Bock in BMC Oral Health (2023)

  5. Article

    Open Access

    Predictive factors and repetition numbers for intraoperative additional resection of initially involved soft tissue resection margins in oral squamous cell carcinoma: a retrospective study

    Intraoperative additional resection (IAR) of initially microscopically involved soft tissue resection margins negatively impacts tumor recurrence in oral squamous cell carcinoma (OSCC). Increasing the selected...

    Mark Ooms, Lisa Ponke, Philipp Winnand in World Journal of Surgical Oncology (2023)

  6. Article

    Open Access

    Attached compared with unattached surface probes for monitoring flap perfusion in microvascular head and neck reconstruction: a feasibility study

    Unattached surface probes are commonly used with the O2C analysis system (LEA Medizintechnik, Germany) to monitor microvascular free flap perfusion. This study compared attached and unattached surface probes f...

    Mark Ooms, Philipp Winnand, Marius Heitzer, Florian Peters, Anna Bock in Scientific Reports (2023)

  7. Article

    Open Access

    Influence of perioperative blood pressure regulation on postoperative delirium in patients undergoing head and neck free flap reconstruction

    Postoperative delirium (POD) is a serious complication in patients undergoing microvascular head and neck reconstruction. Whether intraoperative and postoperative blood pressure regulation are risk factors for...

    Mark Ooms, Ruth Schooß, Philipp Winnand in European Journal of Medical Research (2023)

  8. Article

    Open Access

    Flap perfusion monitoring with an attached surface probe in microvascular reconstruction of the oral cavity

    Postoperative flap monitoring is essential in oral microvascular reconstruction for timely detection of vascular compromise. This study investigated the use of attached surface probes for the oxygen-2-see (O2C...

    Mark Ooms, Philipp Winnand, Marius Heitzer, Florian Peters in Clinical Oral Investigations (2023)

  9. Article

    Open Access

    Assessment of psychological and physical stressors among nurses in different functional areas before and during the COVID-19 pandemic: a cross-sectional study

    The COVID-19 (coronavirus disease) pandemic placed a great burden on all health-care resources, especially nurses. The prevalence and underlying risk factors of affective symptoms related to the COVID-19 pande...

    Philipp Winnand, Yvonne Fait, Mark Ooms, Anna Bock, Marius Heitzer in BMC Nursing (2023)

  10. Article

    Open Access

    Impacts of vascular comorbidities on free flap perfusion in microvascular head and neck reconstruction

    Arterial hypertension (AHTN), type 2 diabetes mellitus (DM), and atherosclerotic vascular disease (ASVD) are common vascular comorbidities in patients undergoing reconstruction of the head and neck region with...

    Mark Ooms, Marius Heitzer, Philipp Winnand in European Archives of Oto-Rhino-Laryngology (2023)

  11. Article

    Open Access

    Comparison of [99mTc]Tc-tilmanocept with [99mTc]Tc-sulphur colloids and [99mTc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head

    Sentinel lymph node (SLN) biopsy is a staging procedure in the management of cutaneous malignancies of the head. The ideal radiopharmaceutical is controversial. This study aimed to compare [99mTc]Tc-tilmanocept (...

    Mark Ooms, Dirk von Mallek in European Journal of Nuclear Medicine and M… (2023)

  12. Article

    Open Access

    Head and neck squamous cell carcinoma: a potential therapeutic target for the Wnt signaling pathway

    Squamous cell carcinoma (SCC) of the head and neck region accounts for 3% of all tumors worldwide. The incidence is higher in men, with most carcinomas found in the oral cavity. At the point of initial diagnos...

    Khosrow Siamak Houschyar, Mimi R. Borrelli in European Journal of Plastic Surgery (2022)

  13. No Access

    Article

    Wnt ligand expression in malignant melanoma: new insights

    Cutaneous melanoma is the deadliest skin cancer and shows an increasing incidence. Survival rates of melanomas without metastases are high, but once metastases develop, mortality rates rise significantly. The ...

    Khosrow Siamak Houschyar, Mimi R. Borrelli in European Journal of Plastic Surgery (2022)

  14. Article

    Open Access

    Smoking and microvascular free flap perfusion in head and neck reconstruction: radial free forearm flaps and anterolateral thigh flaps

    Head and neck reconstruction with microvascular free flaps is frequently performed in smokers. Smoking causes various alterations in the cardiovascular system. The aim of this study was to investigate the effe...

    Mark Ooms, Behrus Puladi, Khosrow Siamak Houschyar, Marius Heitzer in Scientific Reports (2022)