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Article
Changes in white adipose tissue gene expression in a randomized control trial of dieting obese men with lowered serum testosterone alone or in combination with testosterone treatment
The aim of this study was to determine early weight loss-associated changes in subcutaneous abdominal white adipose tissue (WAT) gene expression in obese men with lowered serum testosterone by RNA next-generat...
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Article
A body shape index (ABSI) reflects body composition changes in response to testosterone treatment in obese men
Interventions such as testosterone treatment may change body composition and metabolic outcomes without substantial changes in weight and BMI.
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Article
Open AccessEffect of testosterone treatment on bone remodelling markers and mineral density in obese dieting men in a randomized clinical trial
To assess the effect of testosterone treatment on bone remodelling and density in dieting obese men, 100 obese men aged 53 years (interquartile range 47–60) with a total testosterone level <12 nmol/L receiving...
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Article
Open AccessEffects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet: a randomised controlled trial
Whether testosterone treatment has benefits on body composition over and above caloric restriction in men is unknown. We hypothesised that testosterone treatment augments diet-induced loss of fat mass and prev...
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Article
A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma
Congenital polycythemias have diverse etiologies, including mutations in the hypoxia sensing pathway. These include HIF2A at exon 12, VHL gene (Chuvash polycythemia), and PHD2 mutations, which in one family was a...
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Chapter
Kennedy’s Disease
Kennedy’ s disease (KD) or spinobulbar muscular atrophy is a hereditary X-linked, progressive neurodegenerative condition caused by an expansion of the CAG triplet repeat in the first exon of the androgen rece...