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Open AccessCorrection: Triple MAPK inhibition salvaged a relapsed post-BCMA CAR-T cell therapy multiple myeloma patient with a BRAF V600E subclonal mutation
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Open AccessPublisher Correction: A pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements
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Open AccessA pipeline for malignancy and therapy agnostic assessment of cancer drug response using cell mass measurements
Functional precision medicine offers a promising complement to genomics-based cancer therapy guidance by testing drug efficacy directly on a patient’s tumor cells. Here, we describe a workflow that utilizes si...
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Article
Open AccessTriple MAPK inhibition salvaged a relapsed post-BCMA CAR-T cell therapy multiple myeloma patient with a BRAF V600E subclonal mutation
Multiple Myeloma (MM) is a progressive plasma cell neoplasm characterized by heterogeneous clonal expansion. Despite promising response rates achieved with anti-BCMA CAR-T cell therapy, patients may still rela...
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Open AccessTransmission of Metarhizium anisopliae and Beauveria bassiana to adults of Kuschelorhynchus macadamiae (Coleoptera: Curculionidae) from infected adults and conidiated cadavers
Kuschelorhynchus macadamiae is a major pest of macadamias in Australia, causing yield losses of up to 15%. Our previous studies have shown the weevil is susceptible to Beauveria bassiana and Metarhizium anisoplia...
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Open AccessAuthor Correction: Cooperative nutrient accumulation sustains growth of mammalian cells
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessLinking single-cell measurements of mass, growth rate, and gene expression
Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and ...
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Article
Open AccessMicrofluidic active loading of single cells enables analysis of complex clinical specimens
A fundamental trade-off between flow rate and measurement precision limits performance of many single-cell detection strategies, especially for applications that require biophysical measurements from living ce...
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Open AccessDetermining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
Multiple myeloma (MM) has benefited from significant advancements in treatment that have improved outcomes and reduced morbidity. However, the disease remains incurable and is characterized by high rates of dr...
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Article
Attraction of Parastethorus nigripes and other insect species to methyl salicylate and (Z)-3-hexenyl acetate dispensers in a citrus grove and vineyard in south-eastern Australia
Herbivore-induced plant volatiles (HIPVs) play an important role in tritrophic interactions, and have the potential to attract beneficial arthropods into crops to enhance biological control of target pests. We...
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Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate
The efficacy of cancer drugs is profiled by measuring changes in the mass of single tumor cells.
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High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays
Heterogeneity in growth phenotypes and drug susceptibility in bacterial and mammalian cells are assayed at the single-cell level using multiplexed resonant mass sensors.
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Open AccessCooperative nutrient accumulation sustains growth of mammalian cells
The coordination of metabolic processes to allow increased nutrient uptake and utilization for macromolecular synthesis is central for cell growth. Although studies of bulk cell populations have revealed impor...
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Screening of tropical isolates of Metarhizium anisopliae (Hypocreales: Clavicipitaceae) for virulence to the sweet potato weevil, Cylas formicarius (Coleoptera: Brentidae)
The sweet potato weevil (SPW), Cylas formicarius, is a serious pest of sweet potato in Australia and Papua New Guinea. Ten strains of Metarhizium sp. isolated from Australian soil samples were evaluated for their...
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Toxicity of the Insecticide Terbufos, its Oxidation Metabolites, and the Herbicide Atrazine in Binary Mixtures to Ceriodaphnia cf dubia
The acute toxicity of terbufos and its major metabolites, tested alone, in binary mixtures or in combination with atrazine were evaluated using neonates of the cladoceran Ceriodaphnia cf dubia. Terbufos, terbufos...
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Influence of riparian condition on aquatic macroinvertebrate communities in an agricultural catchment in south-eastern Australia
Riparian vegetation is known to affect aquatic macroinvertebrate communities through contributions of organic matter and shading. Despite the widespread degradation of riparian vegetation in Australia, there a...
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A low concentration of atrazine does not influence the acute toxicity of the insecticide terbufos or its breakdown products to Chironomus tepperi
The acute toxicities of the insecticide terbufos and its major breakdown products individually, as binary mixtures, and in combination with the co-applied herbicide atrazine were evaluated using final instar l...
