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Article
Therapeutische Immunisierungen gegen Tumore und neurodegenerative Erkrankungen
Therapeutische Impfstoffe sollen die körpereigene Immunabwehr bei bereits bestehenden Erkrankungen aktivieren.
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Article
Pharmacokinetic drug–drug interaction between ethinyl estradiol and gestodene, administered as a transdermal fertility control patch, and two CYP3A4 inhibitors and a CYP3A4 substrate
Pharmacokinetic (PK) interactions between the cytochrome P450 3A4 (CYP3A4) pathway and transdermally administered ethinyl estradiol (EE) and gestodene (GSD) were investigated. This paper reports the findings o...
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Article
Vitamin D receptor haplotypes protect against development of colorectal cancer
We investigated the association of vitamin D receptor polymorphisms and colorectal cancer incidence in a Caucasian population.
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Article
Effect of Genetic Polymorphisms in Cytochrome P450 (CYP) 2C9 and CYP2C8 on the Pharmacokinetics of Oral Antidiabetic Drugs
Type 2 diabetes mellitus affects up to 8% of the adult population in Western countries. Treatment of this disease with oral antidiabetic drugs is characterised by considerable interindividual variability in ph...