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  1. Article

    Open Access

    Metabolic changes in response to varying whole-grain wheat and rye intake

    Epidemiological studies have shown associations between whole-grain intake and lowered disease risk. A sufficient level of whole-grain intake to reach the health benefits has not been established, and there is...

    Ville M. Koistinen, Sumanto Haldar, Marjo Tuomainen, Marko Lehtonen in npj Science of Food (2024)

  2. Article

    Open Access

    Side-stream products of malting: a neglected source of phytochemicals

    Whole grain consumption reduces the risk of several chronic diseases. A major contributor to the effect is the synergistic and additive effect of phytochemicals. Malting is an important technological method to...

    Ville M. Koistinen, Marjo Tuomainen, Pekka Lehtinen, Petri Peltola in npj Science of Food (2020)

  3. Article

    Open Access

    Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes

    Despite epidemiological evidence showing that diets rich in whole grains reduce the risk of chronic life-style related diseases, biological mechanisms for these positive effects are mostly unknown. Increased 5...

    Olli Kärkkäinen, Tomi Tuomainen, Ville Koistinen, Marjo Tuomainen in Scientific Reports (2018)

  4. Article

    Open Access

    Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals

    We recently reported using non-targeted metabolic profiling that serum indolepropionic acid (IPA), a microbial metabolite of tryptophan, was associated with a lower likelihood of develo** type 2 diabetes (T2...

    Marjo Tuomainen, Jaana Lindström, Marko Lehtonen, Seppo Auriola in Nutrition & Diabetes (2018)

  5. No Access

    Article

    Characterization of the glyoxalase 1 gene TcGLX1 in the metal hyperaccumulator plant Thlaspi caerulescens

    Stress tolerance is currently one of the major research topics in plant biology because of the challenges posed by changing climate and increasing demand to grow crop plants in marginal soils. Increased Zn tol...

    Marjo Tuomainen, Viivi Ahonen, Sirpa O. Kärenlampi, Henk Schat, Tanja Paasela in Planta (2011)