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Article
Open AccessDirected ultrafast conformational changes accompany electron transfer in a photolyase as resolved by serial crystallography
Charge-transfer reactions in proteins are important for life, such as in photolyases which repair DNA, but the role of structural dynamics remains unclear. Here, using femtosecond X-ray crystallography, we rep...
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Article
Open AccessOptical control of ultrafast structural dynamics in a fluorescent protein
The photoisomerization reaction of a fluorescent protein chromophore occurs on the ultrafast timescale. The structural dynamics that result from femtosecond optical excitation have contributions from vibration...
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Article
Open AccessMonitoring of carbon-water fluxes at Eurasian meteorological stations using random forest and remote sensing
Simulating the carbon-water fluxes at more widely distributed meteorological stations based on the sparsely and unevenly distributed eddy covariance flux stations is needed to accurately understand the carbon-...
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Article
Open AccessHeterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam
For decades, researchers have elucidated essential enzymatic functions on the atomic length scale by tracing atomic positions in real-time. Our work builds on possibilities unleashed by mix-and-inject serial c...
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Article
Open AccessJoint optimization of land carbon uptake and albedo can help achieve moderate instantaneous and long-term cooling effects
Both carbon dioxide uptake and albedo of the land surface affect global climate. However, climate change mitigation by increasing carbon uptake can cause a warming trade-off by decreasing albedo, with most res...
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Article
Standardized maximin D- and c-optimal designs for the Poisson–Gamma model
The Poisson–Gamma model is obtained as a generalization of the Poisson model, when Gamma distributed block effects are assumed for Poisson count data. We show that optimal designs for estimating linear combina...
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Article
On the Use of LES and 3D Empirical Mode Decomposition for Analyzing Cycle-to-Cycle Variations of In-Cylinder Tumbling Flow
Multi-cycle large-eddy simulation (LES) is performed to investigate cycle-to-cycle variations (CCV) of in-cylinder flow in a single-cylinder spark ignition optically-accessible research engine under motored co...
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Article
Open AccessExperimental characterization of the turbulent intake jet in an engine flow bench
The turbulent intake flow of an optically accessible internal combustion engine is modeled using an air flow bench to reduce the complexity in the number of variables inherent within engine flows. By removing ...
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Article
Open AccessThe Influence of Flow on Cycle-to-Cycle Variations in a Spark-Ignition Engine: A Parametric Investigation of Increasing Exhaust Gas Recirculation Levels
Cyclic variability is investigated in an optically accessible single-cylinder spark-ignition research engine by introducing artificial exhaust gas in controlled amounts to the homogenous air–fuel mixture befor...
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Article
Open AccessEffects of Measurement Height and Low-Pass-Filtering Corrections on Eddy-Covariance Flux Measurements Over a Forest Clearing with Complex Vegetation
Flux measurements over heterogeneous surfaces with growing vegetation and a limited fetch are a difficult task, as measurement heights that are too high or too low above the canopy adversely affect results. Th...
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Article
Open AccessRidge-type roughness: from turbulent channel flow to internal combustion engine
While existing engineering tools enable us to predict how homogeneous surface roughness alters drag and heat transfer of near-wall turbulent flows to a certain extent, these tools cannot be reliably applied fo...
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Article
Macromolecular movies, storybooks written by nature
Twelve years ago, the first free electron laser for hard X-rays (XFEL), the Linac Coherent Light Source (LCLS), came online. Due to the extreme brilliance and the ultrashort pulse duration of their X-ray radia...
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Article
Open AccessSynchronous RNA conformational changes trigger ordered phase transitions in crystals
Time-resolved studies of biomacromolecular crystals have been limited to systems involving only minute conformational changes within the same lattice. Ligand-induced changes greater than several angstroms, how...
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Article
Open AccessAuthor Correction: The FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data
A Correction to this paper has been published: https://doi.org/10.1038/s41597-021-00851-9.
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Article
Open AccessNear-Wall Flame and Flow Measurements in an Optically Accessible SI Engine
Near-wall processes in internal combustion engines strongly affect heat transfer and pollutant emissions. With continuously improving capabilities to model near-wall processes, the demand for corresponding mea...
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Chapter and Conference Paper
Novel Insight into Engine Near-Wall Flows and Wall Heat Transfer Using Direct Numerical Simulations and High-Fidelity Experiments
This study combines advanced optical diagnostics and high-fidelity Direct Numerical Simulations (DNS) to deepen the understanding of wall heat transfer processes in Otto engines under motored and fired conditi...
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Article
Open AccessThe FLUXNET2015 dataset and the ONEFlux processing pipeline for eddy covariance data
The FLUXNET2015 dataset provides ecosystem-scale data on CO2, water, and energy exchange between the biosphere and the atmosphere, and other meteorological and biological measurements, from 212 sites around the g...
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Article
Open AccessAuthor Correction: Membrane protein megahertz crystallography at the European XFEL
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Time-resolved serial femtosecond crystallography at the European XFEL
The European XFEL (EuXFEL) is a 3.4-km long X-ray source, which produces femtosecond, ultrabrilliant and spatially coherent X-ray pulses at megahertz (MHz) repetition rates. This X-ray source has been designed...
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Article
Open AccessMembrane protein megahertz crystallography at the European XFEL
The world’s first superconducting megahertz repetition rate hard X-ray free-electron laser (XFEL), the European XFEL, began operation in 2017, featuring a unique pulse train structure with 886 ns between pulse...
