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    Article

    T cell responses to tumor: how dominant assumptions on immune activity led to a neglect of pathological functions, and how evolutionary considerations can help identify testable hypotheses for improving immunotherapy

    Cancer immunotherapy is based on the premise that activated, pro-inflammatory T cell responses to tumor will mostly combat tumor growth. Nowadays accepted as largely valid, this hypothesis has been formed as a...

    Marinos Kallikourdis in Cancer Immunology, Immunotherapy (2018)

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    Chapter

    Chemokines and T Cell Trafficking into Tumors: Strategies to Enhance Recruitment of T Cells into Tumors

    Chemokines are small proteins used by the cells of the immune system in order to orchestrate their movement in the body during physiological and pathological conditions. Yet they are also expressed in tumors a...

    Stefano Garetto, Claudia Sardi, Diego Morone… in Defects in T Cell Trafficking and Resistan… (2016)