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    Chapter

    The WHIM Syndrome

    The WHIM syndrome is a rare immunodeficiency characterized by Warts, Hypogammaglobulinemia, recurrent respiratory bacterial Infections, and Myelokathexis. Early studies identified that neutrophils in WHIM pati...

    Giuliana Roselli, Marinos Kallikourdis in Humoral Primary Immunodeficiencies (2019)

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    Article

    Regulatory T cells mediate maternal tolerance to the fetus

    Pregnancy constitutes a major challenge to the maternal immune system, as it has to tolerate the persistence of paternal alloantigen. Although localized mechanisms contribute to fetal evasion from immune attac...

    Varuna R Aluvihare, Marinos Kallikourdis, Alexander G Betz in Nature Immunology (2004)

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    Article

    B cells and professional APCs recruit regulatory T cells via CCL4

    Using gene expression profiling, we show here that activation of B cells and professional antigen-presenting cells (APCs) induces the expression of common chemokines. Among these, CCL4 was the most potent chem...

    Richard S. Bystry, Varuna Aluvihare, Katie A. Welch in Nature Immunology (2001)