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Article
A directory for neonatal intensive care: potential for facilitating network-based research in neonatology
Directories of contact information have evolved over time from thick paperback times such as the “Yellow Pages” to electronic forms that are searchable and have other functionalities. In our clinical specialty...
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Article
Report of an International Conference on the Medical and Ethical Management of the Neonate at the Edge of Viability: A Review of Approaches from Five Countries
Current United States guidelines for neonatal resuscitation note that there is no mandate to resuscitate infants in all situations. For example, the fetus that at the time of delivery is determined to be so pr...
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Article
1803 PRETERM BABOONS DEMONSTRATE SIGNIFICANT IMPROVEMENT IN OPENING PRESSURES DURING PROGRESSION AND RECOVERY FROM HYALINE MEMBRANE DISEASE (HMD)
High opening pressures (OP) are characteristic of HMD; a reduction in OP may indicate improvement in alveolar stability. Animals were delivered abdominally, and ventilated with either conventional or high freq...
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Article
43 DEVELOPMENTAL OUTCOME AT 1 YR. OF VERY LOW A BIRTHWEIGHT (VLBW) INBORN NEONATES OF LOW-INCOME FAMILIES
The efficacy of neonatal intensive care for the VLBW (≤1250 gm) infant has been infrequently evaluated in low-income populations because of poor compliance and incomplete patient retrieval. All VLBW infants bo...
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Article
1802 PULMONARY FUNCTION TESTS (PFTs) IN PRETERM BABOONS WITH HYALINE MEMBRANE DISEASE (HMD): PROGRESSION AND RECOVERY
Serial PFTs were performed in a baboon model to characterize changes during the course and recovery of HMD. Preterm baboons delivered abdominally at 140±2 days gestation were intubated at birth and stabilized....
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Article
1737 FUNCTIONAL RESIDUAL CAPACITY (FRC) CHANGES IN PRETERM BABOONS WITH HYALINE MEMBRANE DISEASE (HMD)
FRC, related to alveolar stability at end expiration, would be expected to improve with recovery from HMD. Intubated, paralyzed preterm (140±2 days) baboons with HMD were evaluated with serial FRC measurements...
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Article
1651 THE PRETERM BABOON WITH HYALINE MEMBRANE DISEASE (HMD) AS A MODEL FOR BRONCHOPULMONARY DYSPLASIA (BPD)
BPD could be produced clinically and confirmed pathologically in preterm neonatal baboons (Papio cynocephalus) with HMD who were supported with mechanical ventilation (IPPV) and treated with 100% O2 for >1 week. ...
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Article
Fetal and Maternal Hormonal Response to Starvation in the Ewe
Summary: Five ewes 90–130 days of gestation with chronically indwelling fetal catheters were studied. Blood samples were drawn each morning simultaneously from the maternal femoral artery, fetal femoral artery...
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Article
Effect of Epidermal Growth Factor on Lung Maturation in Fetal Rabbits
Summary: Injection of epidermal growth factor (EGF) into 24-day rabbit fetuses (5 μg, im or ip) induced accelerated maturation of the lung. On sacrifice at day 27, there was greater distensibility and stabilit...
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Article
LARYNGEAL CHEMOREFLEX - NEWBORN APNEA AND SUDDEN INFANT DEATH SYNDROME (SIDS)
The coordinated interaction of breathing and swallowing which is developed by 32-34 weeks human gestation is reflex in nature. Chenosensitivity of the laryngeal area can be shown to influence this interaction....
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Article
INCREASED PULMONARY BLOOD FLOW (PBF) DURING ACTH INFUSION IN FETAL LAMBS
ACTH, when given to fetal lambs, will promote pulmonary epithelial maturation and protect the preterm lamb from develo** hyaline membrane disease (HMD). To investigate the possibility that ACTH also acts on ...
