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Open AccessPlatelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study
Circulating extracellular vesicles (EVs) are increased in preeclampsia (PE) and are associated with severity and progression. We examined in this exploratory cohort study if the mRNAs and long noncoding RNAs (...
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Article
Open AccessPlacenta-derived proteins across gestation in healthy pregnancies—a novel approach to assess placental function?
Placenta-derived proteins in the systemic maternal circulation are suggested as potential biomarkers for placental function. However, the identity and longitudinal patterns of such proteins are largely unknown...
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Article
Open AccessAuthor Correction: Dysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women develo** preeclampsia-possible link to enhanced senescence
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Article
Open AccessDysregulated non-coding telomerase RNA component and associated exonuclease XRN1 in leucocytes from women develo** preeclampsia-possible link to enhanced senescence
Senescence in placenta/fetal membranes is a normal phenomenon linked to term parturition. However, excessive senescence which may be induced by telomere attrition, has been associated with preeclampsia (PE). W...
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Article
Open AccessLow CETP activity and unique composition of large VLDL and small HDL in women giving birth to small-for-gestational age infants
Cholesteryl ester transfer protein (CETP) regulates high density lipoproteins (HDL)-cholesterol (C) and HDL-C is essential for fetal development. We hypothesized that women giving birth to large-for-gestationa...
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Open AccessPrediction of Gestational Diabetes Mellitus and Pre-diabetes 5 Years Postpartum using 75 g Oral Glucose Tolerance Test at 14–16 Weeks’ Gestation
Early detection and treatment of women at risk for gestational diabetes mellitus (GDM) could improve perinatal and long-term outcomes in GDM women and their offspring. We explored if a 75 g oral glucose tolera...
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Open AccessGene expression in term placentas is regulated more by spinal or epidural anesthesia than by late-onset preeclampsia or gestational diabetes mellitus
Pre-eclampsia (PE) and gestational diabetes mellitus (GDM) are common complications of pregnancy, but the mechanisms underlying these disorders remain unclear. The aim was to identify the extent of altered gen...