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Article
Open AccessReported outcomes in patients with iron deficiency or iron deficiency anemia undergoing major surgery: a systematic review of outcomes
Iron deficiency (ID) is the leading cause of anemia worldwide. The prevalence of preoperative ID ranges from 23 to 33%. Preoperative anemia is associated with worse outcomes, making it important to diagnose an...
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Article
Open AccessPublic information needs and preferences on COVID-19: a cross-sectional study
Right from the beginning of the SARS-CoV-2 pandemic the general public faced the challenge to find reliable and understandable information in the overwhelming flood of information. To enhance informed decision...
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Article
Open AccessCOVID-19-Pandemie: Präferenzen und Barrieren für die Disseminierung von Evidenzsynthesen
Das COVID-19-Evidenz-Ökosystem (CEOsys) identifiziert, bewertet und fasst Ergebnisse wissenschaftlicher Studien in Evidenzsynthesen im Kontext von COVID-19 zusammen. Diese Evidenzsynthesen werden genutzt, um k...
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Article
Open AccessTrial registration and selective outcome reporting in 585 clinical trials investigating drugs for prevention of postoperative nausea and vomiting
Selective outcome reporting in clinical trials introduces bias in the body of evidence distorting clinical decision making. Trial registration aims to prevent this bias and is suggested by the International Co...
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Article
Open AccessSelective blood-nerve barrier leakiness with claudin-1 and vessel-associated macrophage loss in diabetic polyneuropathy
Diabetic polyneuropathy (DPN) is the most common complication in diabetes and can be painful in up to 26% of all diabetic patients. Peripheral nerves are shielded by the blood-nerve barrier (BNB) consisting of...
