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Chapter
Current Methods for Intraoperative Application
Breast cancer is the most common cancer in women worldwide. Since 2008, worldwide breast cancer incidence has increased by more than 20%, whilst mortality has increased by 14%. The current gold standard in bre...
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Article
Open AccessAlzheimer's disease diagnosis by blood plasma molecular fluorescence spectroscopy (EEM)
Despite tremendous research advances in detecting Alzheimer's disease (AD), traditional diagnostic tests remain expensive, time-consuming or invasive. The search for a low-cost, rapid, and minimally invasive t...
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Article
Open AccessThe vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia
Vaginal microbiota (VMB) composition is altered in women with cervical intra-epithelial neoplasia (CIN) compared to healthy controls and is associated with disease progression. However, the impact of CIN excis...
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Article
Open AccessNew approach to investigate Common Variable Immunodeficiency patients using spectrochemical analysis of blood
Common variable immune deficiency (CVID) is a primary immunodeficiency disease, characterized by hypogammaglobulinemia, recurrent infections and various complications. The clinical heterogeneity of CVID has hi...
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Article
Standardization of complex biologically derived spectrochemical datasets
Spectroscopic techniques such as Fourier-transform infrared (FTIR) spectroscopy are used to study interactions of light with biological materials. This interaction forms the basis of many analytical assays use...
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Article
Open AccessVibrational spectroscopy: a promising approach to discriminate neurodegenerative disorders
Neurodegenerative diseases are a growing burden in modern society, thus crucially calling for the development of accurate diagnostic strategies. These diseases are currently incurable, a fact which has been at...
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Chapter
ATR-FTIR Spectroscopy Tools for Medical Diagnosis and Disease Investigation
Vibrational spectroscopic techniques are increasingly utilized in biomedical research. Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy has been applied extensively to investigate...
