5 Result(s)

Article

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

RNA interference (RNAi) screening is a state-of-the-art technology that enables the dissection of biological processes and disease-related phenotypes. The commercial availability of genome-wide, short hairpin ...

David Sims, Ana M Mendes-Pereira, Jessica Frankum, Darren Burgess… in Genome Biology (2011)

Article

DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer

The APOBEC3 family of cytidine deaminases mutate the cancer genome in a range of cancer types. Although many studies have documented the downstream effects of APOBEC3 activity through next-generation sequencin...

Nnennaya Kanu, Maria Antonietta Cerone, Gerald Goh… in Genome Biology (2016)

Article

Publisher Correction: The National Lung Matrix Trial of personalized therapy in lung cancer

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Gary Middleton, Peter Fletcher, Sanjay Popat, Joshua Savage, Yvonne Summers… in Nature (2020)

Article

The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care

Genomic screening is routinely used to guide the treatment of cancer patients in many countries. However, several multi-layered factors make this effort difficult to deliver within a clinically relevant timefr...

Maria Antonietta Cerone, Tara C. Mills, Rowena Sharpe… in British Journal of Cancer (2023)

Article

Correction to: The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care

Maria Antonietta Cerone, Tara C. Mills, Rowena Sharpe… in British Journal of Cancer (2023)