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  1. Article

    Open Access

    Assessing the potential for improved predictive capacity of antimicrobial resistance in outpatient Staphylococcus aureus isolates using seasonal and spatial antibiograms

    While the use of cumulative susceptibility reports, antibiograms, is recommended for improved empiric therapy and antibiotic stewardship, the predictive ability of antibiograms has not been well-studied. While...

    Margaret Carrel, Qianyi Shi, Gosia S. Clore in Antimicrobial Resistance & Infection Contr… (2024)

  2. Article

    Open Access

    Epidemiology of Plasmodium malariae and Plasmodium ovale spp. in Kinshasa Province, Democratic Republic of Congo

    Reports suggest non-falciparum species are an underappreciated cause of malaria in sub-Saharan Africa but their epidemiology is ill-defined, particularly in highly malaria-endemic regions. We estimated inciden...

    Rachel Sendor, Kristin Banek, Melchior M. Kashamuka, Nono Mvuama in Nature Communications (2023)

  3. Article

    Open Access

    Spatial and temporal trends of overweight/obesity and tobacco use in East Africa: subnational insights into cardiovascular disease risk factors

    Cardiovascular disease (CVD) is increasing in Sub-Saharan Africa (SSA). Overweight/obesity and tobacco use are modifiable CVD risk factors, however literature about the spatiotemporal dynamics of these risk fa...

    Barbara Chebet Keino, Margaret Carrel in International Journal of Health Geographics (2023)

  4. Article

    Open Access

    The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo

    Drug resistant malaria is a growing concern in the Democratic Republic of the Congo (DRC), where previous studies indicate that parasites resistant to sulfadoxine/pyrimethamine or chloroquine are spatially clu...

    Molly Deutsch-Feldman, Ozkan Aydemir, Margaret Carrel in BMC Infectious Diseases (2019)

  5. Article

    Open Access

    Correction to: Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo

    Unfortunately after publication of the original article [1], it came to the author’s attention that there is an error in the caption of Fig. 2.

    Melchior Kashamuka Mwandagalirwa, Lauren Levitz, Kyaw L. Thwai in Malaria Journal (2018)

  6. Article

    Open Access

    Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates

    Avian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness in, and thus ...

    Sean G. Young, Andrew Kitchen, Ghazi Kayali, Margaret Carrel in BMC Infectious Diseases (2018)

  7. Article

    Open Access

    Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo

    The Democratic Republic of the Congo (DRC) bears a large share of global malaria burden despite efforts to control and eliminate the disease. More detailed understanding of individual and household level chara...

    Melchior Kashamuka Mwandagalirwa, Lauren Levitz, Kyaw L. Thwai in Malaria Journal (2017)

  8. Article

    Open Access

    Assessing the potential for raw meat to influence human colonization with Staphylococcus aureus

    The role of household meat handling and consumption in the transfer of Staphylococcus aureus (S. aureus) from livestock to consumers is not well understood. Examining the similarity of S. aureus colonizing humans...

    Margaret Carrel, Chang Zhao, Dipendra Thapaliya, Patrick Bitterman in Scientific Reports (2017)

  9. Article

    Open Access

    Diffusion of clindamycin-resistant and erythromycin-resistant methicillin-susceptible Staphylococcus aureus (MSSA), potential ST398, in United States Veterans Health Administration Hospitals, 2003-2014

    Changing phenotypic profiles of methicillin-susceptible Staphylococcus aureus (MSSA) isolates can indicate the emergence of novel sequence types (ST). The diffusion of MSSA ST can be tracked by combining establis...

    Margaret Carrel, Michihiko Goto in Antimicrobial Resistance & Infection Contr… (2017)

  10. Article

    Open Access

    Regional variations in fluoroquinolone non-susceptibility among Escherichia coli bloodstream infections within the Veterans Healthcare Administration

    We sought to define regional variations in fluoroquinolone non-susceptibility (FQ-NS) among bloodstream isolates of Escherichia coli across the Veterans Health Administration (VHA) in the United States.

    Daniel J. Livorsi, Michihiko Goto in Antimicrobial Resistance & Infection Contr… (2016)

  11. Article

    Open Access

    Molecular characterization of methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization and infection isolates in a Veterans Affairs hospital

    Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) is associated with increased infection risk, yet colonization and infection isolates are rarely compared within the same study. The objec...

    Kalyani E Eko, Brett M Forshey in Antimicrobial Resistance and Infection Con… (2015)

  12. No Access

    Article

    Highly Pathogenic H5N1 Avian Influenza Viruses Exhibit Few Barriers to Gene Flow in Vietnam

    Locating areas where genetic change is inhibited can illuminate underlying processes that drive evolution of pathogens. The persistence of highly pathogenic H5N1 avian influenza in Vietnam since 2003, and the ...

    Margaret Carrel, **u-Feng Wan, Tung Nguyen, Michael Emch in EcoHealth (2012)

  13. Article

    Open Access

    Diarrheal disease risk in rural Bangladesh decreases as tubewell density increases: a zero-inflated and geographically weighted analysis

    This study investigates the impact of tubewell user density on cholera and shigellosis events in Matlab, Bangladesh between 2002 and 2004. Household-level demographic, health, and water infrastructure data wer...

    Margaret Carrel, Veronica Escamilla in International Journal of Health Geographics (2011)

  14. Article

    Open Access

    Protection from annual flooding is correlated with increased cholera prevalence in Bangladesh: a zero-inflated regression analysis

    Alteration of natural or historical aquatic flows can have unintended consequences for regions where waterborne diseases are endemic and where the epidemiologic implications of such change are poorly understoo...

    Margaret Carrel, Paul Voss, Peter K Streatfield, Mohammad Yunus in Environmental Health (2010)