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  1. Article

    Open Access

    Quantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease

    Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause o...

    Marco Hadisurya, Li Li, Kananart Kuwaranancharoen, **aofeng Wu… in Communications Medicine (2023)

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  2. No Access

    Protocol

    Isolation and Identification of Plasma Extracellular Vesicles Protein Biomarkers

    (EVs) have emerged as a valuable source for disease and an alternative drug delivery system due to their ability to carry cargo and target specific cells. Proper isolation, identification, and analytical st...

    Michelle V. Lihon, Marco Hadisurya, **aofeng Wu… in Cancer Systems and Integrative Biology (2023)

  3. Article

    Open Access

    Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

    Pancreatic cancer is one of the most difficult cancers to detect early and most patients die from complications arising due to distant organ metastases. The lack of bona fide early biomarkers is one of the pri...

    Harrys Kishore Charles Jacob… in Journal of Experimental & Clinical Cancer … (2022)

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