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    Article

    Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

    Experimental and epidemiological studies indicate a strong link between chronic inflammation and tumor progression. Human colorectal cancer (CRC), a major cause of cancer-related death in Western countries, re...

    Marco Erreni, Alberto Mantovani, Paola Allavena in Cancer Microenvironment (2011)

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    Heme catabolism by tumor-associated macrophages controls metastasis formation

    Although the pathological significance of tumor-associated macrophage (TAM) heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising anticancer therapy. Here we show that a distinct...

    Francesca Maria Consonni, Augusto Bleve, Maria Grazia Totaro in Nature Immunology (2021)