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Open AccessLegacy of the discovery of the T-cell receptor: 40 years of sha** basic immunology and translational work to develop novel therapies
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Trace Element Concentration in the Blood and Aqueous Humor of Subjects with Eye Cataract
Cataract, characterized by the opacification of the lens, is the leading cause of reversible blindness and visual impairment globally. The study aims to investigate the role of trace elements such as Cd, Co, C...
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Article
Open AccessThe impact of indoor air pollution on children’s health and well-being: the experts’ consensus
Pollution of the indoor environment represents a concern for human health, mainly in case of prolonged exposure such as in the case of women, children, the elderly, and the chronically ill, who spend most of t...
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Article
Risk Characterization of the Armenian Population to Nickel: Application of Deterministic and Probabilistic Approaches to a Total Diet Study in Yerevan City
Nickel (Ni) is a widespread metal that occurs in food and drinking water from both natural and anthropogenic sources. Oral exposure to Ni can induce a variety of adverse effects; the European Food Safety Autho...
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Open AccessAutoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course
Infection with severe acute respiratory syndrome coronavirus 2 associates with diverse symptoms, which can persist for months. While antiviral antibodies are protective, those targeting interferons and other i...
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Article
Macrophages as tools and targets in cancer therapy
Tumour-associated macrophages are an essential component of the tumour microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix remodelling, cancer cell proliferation, metast...
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Open AccessLong Covid: where we stand and challenges ahead
Post-acute sequelae of SARS-CoV-2 (PASC), also known as Post-Covid Syndrome, and colloquially as Long Covid, has been defined as a constellation of signs and symptoms which persist for weeks or months after th...
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Open AccessCorrection: Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
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Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19
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Open AccessImmune response in COVID-19: what is next?
The coronavirus disease 2019 (COVID-19) has been a global pandemic for more than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A better understanding of immunity and its r...
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Open AccessInflammation and neutrophil extracellular traps in cerebral cavernous malformation
Cerebral Cavernous Malformation (CCM) is a brain vascular disease with various neurological symptoms. In this study, we describe the inflammatory profile in CCM and show for the first time the formation of neu...
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Article
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules
The humoral arm of innate immunity includes diverse molecules with antibody-like functions, some of which serve as disease severity biomarkers in coronavirus disease 2019 (COVID-19). The present study was desi...
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Nephrectomy: Robotic Approach
Minimally invasive nephrectomy (laparoscopic and robot-assisted) is performed routinely in adult patients affected by renal tumors or benign conditions.
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Minimally Invasive Treatment of Ureteric Stones in Children
Paediatric nephrolithiasis is seen more and more frequently, with patients often presenting to the emergency department with acute symptoms requiring immediate evaluation and treatment. The pain is usually due...
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Management of Kidney Stones Using RIRS
Renal stone disease is an important increasing clinical problem in pediatric urology practice. Evidences suggest that, although urinary lithiasis is less prevalent in children than in adults, it is associated ...
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Open AccessThe antibody response to SARS-CoV-2 infection persists over at least 8 months in symptomatic patients
Persistence of antibodies to SARS-CoV-2 viral infection may depend on several factors and may be related to the severity of disease or to the different symptoms.
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Correction: Siltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19
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Open AccessSiltuximab downregulates interleukin-8 and pentraxin 3 to improve ventilatory status and survival in severe COVID-19
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Open AccessPentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC), characterized by dense desmoplastic stroma laid down by pancreatic stellate cells (PSC), has no reliable diagnostic biomarkers for timely detection. A multi-center coho...
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Open AccessSerum amyloid P component is an essential element of resistance against Aspergillus fumigatus
Serum amyloid P component (SAP, also known as Pentraxin 2; APCS gene) is a component of the humoral arm of innate immunity involved in resistance to bacterial infection and regulation of tissue remodeling. Here w...
