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  1. No Access

    Protocol

    Assessing the Nanoscale Organization of Excitatory and Inhibitory Synapses Using Recombinant Probes to Visualize Endogenous Synaptic Proteins

    Synapses are highly dynamic and complex structures responsible for neuronal communication. The recent progresses in super-resolution imaging technologies unraveled an inherently complex nanorganization of syna...

    Matteo Fossati, Marco Erreni… in Translational Research Methods in Neurodev… (2022)

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    Article

    Heme catabolism by tumor-associated macrophages controls metastasis formation

    Although the pathological significance of tumor-associated macrophage (TAM) heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising anticancer therapy. Here we show that a distinct...

    Francesca Maria Consonni, Augusto Bleve, Maria Grazia Totaro… in Nature Immunology (2021)

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    Article

    Macrophage polarization in pathology

    Macrophages are cells of the innate immunity constituting the mononuclear phagocyte system and endowed with remarkable different roles essential for defense mechanisms, development of tissues, and homeostasis....

    Antonio Sica, Marco Erreni, Paola Allavena… in Cellular and Molecular Life Sciences (2015)

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    Article

    Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

    Experimental and epidemiological studies indicate a strong link between chronic inflammation and tumor progression. Human colorectal cancer (CRC), a major cause of cancer-related death in Western countries, re...

    Marco Erreni, Alberto Mantovani, Paola Allavena in Cancer Microenvironment (2011)