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  1. No Access

    Protocol

    Assessing the Nanoscale Organization of Excitatory and Inhibitory Synapses Using Recombinant Probes to Visualize Endogenous Synaptic Proteins

    Synapses are highly dynamic and complex structures responsible for neuronal communication. The recent progresses in super-resolution imaging technologies unraveled an inherently complex nanorganization of syna...

    Matteo Fossati, Marco Erreni… in Translational Research Methods in Neurodev… (2022)

  2. No Access

    Article

    Heme catabolism by tumor-associated macrophages controls metastasis formation

    Although the pathological significance of tumor-associated macrophage (TAM) heterogeneity is still poorly understood, TAM reprogramming is viewed as a promising anticancer therapy. Here we show that a distinct...

    Francesca Maria Consonni, Augusto Bleve, Maria Grazia Totaro… in Nature Immunology (2021)

  3. Article

    Open Access

    Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism

    Thyroid carcinoma includes several variants characterized by different biological and clinical features: from indolent microcarcinoma to undifferentiated and aggressive anaplastic carcinoma. Inflammation plays...

    Mara Mazzoni, Giuseppe Mauro, Marco Erreni… in Journal of Experimental & Clinical Cancer … (2019)

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    Article

    Tumor-associated Macrophages (TAM) and Inflammation in Colorectal Cancer

    Experimental and epidemiological studies indicate a strong link between chronic inflammation and tumor progression. Human colorectal cancer (CRC), a major cause of cancer-related death in Western countries, re...

    Marco Erreni, Alberto Mantovani, Paola Allavena in Cancer Microenvironment (2011)