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  1. No Access

    Article

    Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes

    One leading cause of perinatal morbidity and mortality is intrauterine growth restriction (IUGR). Several causes for IUGR have been proposed involving cytotrophoblast dysfunction. Envelope genes of the human e...

    Matthias Ruebner, Pamela L. Strissel, Manuela Langbein… in Journal of Molecular Medicine (2010)

  2. No Access

    Article

    Proliferation and cell–cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin-1 and regulated by TGF-β

    Endometrial carcinomas (EnCa) predominantly represent a steroid hormone-driven tumor initiated from prestages. The human endogenous retrovirus HERV-W envelope gene Syncytin-1 was significantly increased at the...

    Reiner Strick, Sven Ackermann, Manuela Langbein… in Journal of Molecular Medicine (2007)