10 Result(s)
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Host–microbe metabolic dialogue
Metabolomics and feeding experiments demonstrate the host’s active role in sharing organic acids with a gut microbiota member, revealing host–microbe interactions that foster symbiosis.
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Open AccessmicrobeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data
microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 micro...
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Visualization of metabolites and microbes at high spatial resolution using MALDI mass spectrometry imaging and in situ fluorescence labeling
Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous map** of hundreds of different metabolites...
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Open AccessSugars dominate the seagrass rhizosphere
Seagrasses are among the most efficient sinks of carbon dioxide on Earth. While carbon sequestration in terrestrial plants is linked to the microorganisms living in their soils, the interactions of seagrasses ...
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Open AccessDie chemische Sprache von Symbiosen sichtbar machen
Small molecules — metabolites — provide the basis for chemical interactions between hosts and microbes. Especially in animal-microbe symbioses, the close physical interactions require a spatial organization of...
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Verrucomicrobia use hundreds of enzymes to digest the algal polysaccharide fucoidan
Brown algae are important players in the global carbon cycle by fixing carbon dioxide into 1 Gt of biomass annually, yet the fate of fucoidan—their major cell wall polysaccharide—remains poorly understood. Mic...
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Spatial metabolomics of in situ host–microbe interactions at the micrometre scale
Spatial metabolomics describes the location and chemistry of small molecules involved in metabolic phenotypes, defence molecules and chemical interactions in natural communities. Most current techniques are un...
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Open AccessTwo intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2
Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans1,2. Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location a...
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Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN
BATMAN is an R package developed to analyze one-dimensional NMR spectra of complex metabolite mixtures using a user-defined template library.
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Open AccessRole of N-terminal protein formylation in central metabolic processes in Staphylococcus aureus
Bacterial protein biosynthesis usually depends on a formylated methionyl start tRNA but Staphylococcus aureus is viable in the absence of Fmt, the tRNAMet formyl transferase. fmt mutants exhibit reduced growth ra...
