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Article
Open AccessA simple and useful method for evaluation of oxidative stress in vivo by spectrofluorometric estimation of urinary pteridines
Pteridine derivatives are intermediate metabolites of folic acid and its cofactors. Oxidized-form pteridines, but not reduced-form pteridines, are fluorescent substances. The purpose of this study was to clari...
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Article
Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation
Calcium ion (Ca2+) uptake into the mitochondrial matrix influences ATP production, Ca2+ homeostasis, and apoptosis regulation. Ca2+ uptake across the ion-impermeable inner mitochondrial membrane is mediated by th...
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Protocol
Analysis of Neuroimmune Interactions by an In Vitro Coculture Approach
Nerve fibers innervate every organ of the body and are involved in monitoring changes of the external and internal environment. Innervation directly controls a variety of physiological responses in an adaptive...
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Article
Open AccessIdentification of Treatment Efficacy-Related Host Factors in Chronic Hepatitis C by ProteinChip Serum Analysis
Recent development of proteomic array technology, including protein profiling coupling ProteinChip array with surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF/MS), provi...
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Article
Inhibition of degranulation and cytokine production in bone marrow-derived mast cells by hydrolyzed rice bran
We investigated the effects of hydrolyzed rice bran (HRB), an arabinoxylan extracted from rice bran, on mast cell degranulation and cytokine production.
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Article
Pitavastatin Reduces Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Ligands in Hypercholesterolemic Humans
The aim of this study was to determine the impact of pitavastatin on low-density lipoprotein cholesterol (LDL-C) and lectin-like oxidized LDL receptor-1 (LOX-1) in patients with hypercholesterolemia. Twenty-fi...
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Article
Myeloid sarcoma in essential thrombocythemia that transformed into acute myeloid leukemia
A 72-year-old man was diagnosed with essential thrombocythemia (ET) and was treated with hydroxyurea for approximately 5 years. He was well until April 2007. In May 2007, a slight fall in hemoglobin levels was...
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Article
Molecular Basis of Neuroimmune Interaction in an In Vitro Coculture Approach
A team of researchers from Nagoya, Tokyo and Hamilton developed a unique technique for studying neuroimmune interaction with confocal laser scanning fluorescence microscopy several years ago. It relies on guid...
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Article
A New Real Time Object Segmentation and Tracking Algorithm and its Parallel Hardware Architecture
Most of the emerging content-based multimedia technologies are based on efficient methods to solve machine early vision tasks. Among other tasks, object segmentation is perhaps the most important problem in si...
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Article
Cationic Cholesterol Promotes Gene Transfection Using the Nuclear Localization Signal in Protamine
Purpose. The purpose of this study was to evaluate protamine-mediated gene transfection by liposomes with a novel cationic cholesterol derivative (I) compared to those with DC-Chol or DOTMA (Lipofectin).
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Article
Serum protein and immunoglobulin levels among nepalese living in southern Nepal
This study examined the levels of serum protein fractionation, immunoglobulin (Ig) and antistreptolysin O (ASO) of people (91 males and 84 females aged 10–68 years) living in the Terai region of southern Nepal...
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Article
A butter diet induces higher levels of n-3 PUFA and of n−3/n−6 PUFA ratio in rat serum and hearts than a safflower oil diet
The effects of a 47-week diet of butter or safflower oil as fat in combination with casein or soy protein as protein were observed for the serum concentrations of lipids and fatty acid compositions in rat seru...
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Article
Real-time CAM-based Hough transform algorithm and its performance evaluation
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Article
Helicobacter pylori and Mucosal Atrophy in Patients with Gastric Cancer (A Special Study Regarding the Methods for Detecting Helicobacter pylori)
We assessed the sensitivities of several methodsfor detecting Helicobacter pylori (culture, histology,rapid urease test, and serology), and evaluated the H.pylori positivity considering the degree of atrophy i...
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Article
Stopped-flow fluorescence studies on binding of snake neurotoxins to acetylcholine receptor
The stopped-flow technique has been applied to observe the time dependence of a tryptophanyl fluorescence change upon binding of postsynaptic snake neurotoxins to nicotinic acetylcholine receptor (Narke japonica)...